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Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 711-720 of 3452

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  1. Salubrinal
    B2025 Salubrinal
     1 Citation
    Summary: Selective eIF2α inhibitor
      ≥48 mg/mL
  2. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL
  3. WYE-687
    B1638 WYE-687
    Summary: MTOR inhibitor,ATP-competitive and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  4. CP-91149
    A8403 CP-91149
    Target: Glycogen Phosphorylases
    Summary: Selective inhibitor of glycogen phosphorylase
      insoluble in H2O; ≥16.4 mg/mL
  5. IPA-3
    B2169 IPA-3
     1 Citation
    Target: PAK
    Summary: Non-ATP competitive Pak1 inhibitor
      insoluble in H2O; ≥16.1 mg/mL
  6. PJ34
    A3729 PJ34
    Target: PARP
    Summary: PARP-l inhibitor
      ≥50.9 mg/mL
  7. 4-Chlorophenylguanidine hydrochloride
    A4445 4-Chlorophenylguanidine hydrochloride
    Target: Urokinases
    Summary: Urokinase inhibitor, potent and specific
      Soluble to 100 mM in H2O
  8. (±)-CPSI 1306
    B5576 (±)-CPSI 1306
    Summary: macrophage inhibitory factor (MIF) inhibitor
      <31.03 mg/mL
  9. EB 47
    A4528 EB 47
    Summary: Potent PARP-1 inhibitor
      <30.52 mg/mL
  10. Anguizole
    A3182 Anguizole
    Summary: Inhibitor of HCV replication
      Soluble in DMSO

Items 711-720 of 3452

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  1. Biotinylation reagents and kits 1 item
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  19. Cell culture 1 item
  20. Antibody 1 item
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  1. Selective 810item
  2. Non-Selective 5item
Reversibility
  1. Reversible 65item
  2. Irreversible 39item
Target
  1. Caspases 14item
  2. Cyclin-Dependent Kinases 33item
  3. Proteasome 14item
  4. Cathepsins 11item
  5. Histone Deacetylases (HDACs) 37item
  6. Inhibitor of apoptosis proteins (IAP) 2item
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  48. Hydrolase 1 item
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  50. p38 9item
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  53. JNK 7item
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  55. Bcr-Abl 15item
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  57. MEK 16item
  58. PORCN 1 item
  59. DOT1L 3item
  60. FGFR 17item
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  62. Insulin-like growth factor receptors(IGFRs) 1 item
  63. Pim 5item
  64. Sir2-like Family Deacetylases (Sirtuins) 3item
  65. Deubiquitinating enzymes (DUBs) 5item
  66. Smoothened 4item
  67. Neuraminidases (NA) 2item
  68. MET 7item
  69. Src 18item
  70. Trk Receptors 7item
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  76. Microtubules/Tubulins 5item
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  80. ROCK 12item
  81. BTK 2item
  82. RIP kinases 1 item
  83. Monocyte chemotactic proteins 1 item
  84. PAK 3item
  85. PD-1/PD-L1 interaction 1 item
  86. Hypoxia Inducible Factors (HIFs) 2item
  87. Tankyrases 1 item
  88. Inositol Phosphatases 1 item
  89. FAK 7item
  90. BMP and Other Activin Receptors 4item
  91. JAK 22item
  92. p300 1 item
  93. Stearoyl-CoA 9-desaturase (SCD-1) 2item
  94. Syk 7item
  95. EZH1 2item
  96. DNA-PK 8item
  97. HSP90 12item
  98. AMPK 2item
  99. Gutathione S-transferase 2item
  100. PDHK 1 item
  101. Angiotensin AT2 Receptors 1 item
  102. eIF4E/eIF3G interaction 1 item
  103. Notch 1 item
  104. S-nitrosoglutathione reductase 1 item
  105. CFTR 2item
  106. TNKS 1 item
  107. Topoisomerases 14item
  108. Cytochrome P450 (CYP450) 8item
  109. M3 Receptors 1 item
  110. thrombin 1 item
  111. Ksp 2item
  112. Ribosomes 1 item
  113. Renin 2item
  114. HIV proteases 1 item
  115. Pepsins 1 item
  116. Influenza viruses 1 item
  117. ErbB 5item
  118. Ferroptosis 1 item
  119. S6 kinases 1 item
  120. Toll-like receptors (TLRs) 3item
  121. Adenosine Kinases 2item
  122. Actin 2item
  123. Serine Proteases 2item
  124. DNA Methyltransferases 3item
  125. Survivin 1 item
  126. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  127. ERK 8item
  128. HMG-CoA Reductases 6item
  129. Vacuolar-type ATPase 1 item
  130. Kinases 1 item
  131. c-MET 8item
  132. BMI-1 1 item
  133. PKC 15item
  134. Calpains 6item
  135. Ubiquitin-specific proteases 1 item
  136. HCV Proteases 3item
  137. Ca2 /calmodulin-dependent protein kinases (CaMKs) 7item
  138. MLK3 1 item
  139. SMYD2 1 item
  140. O-GlcNAcase 1 item
  141. CREBBP 2item
  142. EP300 2item
  143. Protease-Activated Receptors 1 item
  144. Lyn 2item
  145. SGLT 1 item
  146. RAD51 2item
  147. Trypsins 1 item
  148. HER2 3item
  149. Pyk2 3item
  150. USP 3item
  151. 5-HT2 Receptors 4item
  152. LRRK2 6item
  153. Voltage-gated Calcium Channels (CaV) 2item
  154. DGAT 2item
  155. Insulin and Insulin-like Receptors 4item
  156. PARP 9item
  157. CB1 Receptors 1 item
  158. Melanocortin (MC) Receptors 1 item
  159. Pyruvate dehydrogenases (PDH) 2item
  160. ALK 10item
  161. ROS1 2item
  162. Sphingosine kinases (SphKs) 3item
  163. Trypsin 1 item
  164. Chymotrypsin 1 item
  165. Kallikrein 1 item
  166. Trypsinogen 1 item
  167. KRAS G12C 1 item
  168. GTPases 1 item
  169. Monocarboxylate transporters (MCTs) 2item
  170. CETP 2item
  171. Dehydrogenase 1 item
  172. PKG 3item
  173. PKA 7item
  174. Myosin light chain kinases (MLCKs) 3item
  175. HIV-1 gp120 1 item
  176. D1 and D5 Receptors 1 item
  177. D2 Receptors 3item
  178. D3 Receptors 2item
  179. 5-HT1 Receptors 2item
  180. 5-HT7 Receptors 1 item
  181. CaM-KK 1 item
  182. Valosin-containing protein (VCP) 1 item
  183. MELK 1 item
  184. Serotonin reuptake 1 item
  185. Insulin-like growth factors (IGFs) 1 item
  186. Clk 1 item
  187. TBK1 1 item
  188. MARK1 1 item
  189. NUAK1 2item
  190. Integrin-ligand interactions 1 item
  191. CSF1R 1 item
  192. Bromodomain and Extra-Terminal motif (BET) 1 item
  193. NUAK2 1 item
  194. Na /H Exchangers (NHEs) 1 item
  195. Lactate Dehydrogenases (LDH) 3item
  196. MK2 4item
  197. Fatty-acid-binding proteins (FABPs) 1 item
  198. Angiotensin-Converting Enzymes (ACEs) 6item
  199. Tie-2 5item
  200. RSK 3item
  201. p70 S6K 1 item
  202. Granzyme B 1 item
  203. phosphatases 2item
  204. Autophagy 4item
  205. ATM/ATR 8item
  206. Mixed lineage kinase domain-like protein (MLKL) 1 item
  207. COX 12item
  208. Heparanases 1 item
  209. CK1 2item
  210. IDH2 1 item
  211. CK2 3item
  212. HIPK2 1 item
  213. HIPK3 1 item
  214. HIV Integrases 3item
  215. Squalene epoxidases 2item
  216. PRAK 1 item
  217. MAPKAP-K2 1 item
  218. Delayed rectifier outward potassium current (IKr) 1 item
  219. GpIIb/IIIa receptor 1 item
  220. Guanine nucleotide exchange factors (GEFs) 1 item
  221. 20S proteasomal chymotrypsin 1 item
  222. Geranylgeranyltransferase I 1 item
  223. Farnesyltransferase 1 item
  224. NAT10 1 item
  225. Nampt 3item
  226. eIF4F 1 item
  227. Cdc42 1 item
  228. SRPK1 1 item
  229. P2X Receptors 1 item
  230. Glutaminases 2item
  231. Carbonic Anhydrases 7item
  232. Ron 1 item
  233. AP endonucleases 1 item
  234. G9a 2item
  235. BLM 1 item
  236. HSV 2item
  237. NADPH Oxidases 3item
  238. Calcium-activated chloride channels (CaCC) 1 item
  239. GPR35 1 item
  240. Urokinases 1 item
  241. Aldehyde Dehydrogenases 1 item
  242. Synthases/Synthetases 3item
  243. MAGL 1 item
  244. c-Fyn 1 item
  245. TAK1 1 item
  246. Histamine H1 Receptors 3item
  247. Na /K ATPases 3item
  248. P110 1 item
  249. Hck 2item
  250. Inositol-requiring enzyme 1 (IRE1) 3item
  251. SETD7 1 item
  252. Na /K /Cl- Symporters (NKCCs) 2item
  253. GABAA Receptors 1 item
  254. Phospholipases 1 item
  255. Monoamine oxidases (MAOs) 1 item
  256. Organic anion transporters (OATs) 1 item
  257. TRP Channel 1 item
  258. RNA Polymerases 2item
  259. DYRK 2item
  260. Norepinephrine transporter 1 item
  261. 5-HT Transporters 3item
  262. Xanthine oxidoreductases 1 item
  263. Dihydroorotate dehydrogenase 1 item
  264. Histone Demethylases 1 item
  265. MNK 2item
  266. 5-Lipoxygenases 1 item
  267. NO Donors / Precursors 2item
  268. CB2 Receptors 1 item
  269. HIV-1 reverse transcriptase 1 item
  270. IL Receptors 2item
  271. CCL2 1 item
  272. Noradrenaline reuptake 1 item
  273. Norepinephrine transporters 1 item
  274. Calcium-Activated Potassium (KCa) Channels 2item
  275. AChE 3item
  276. Insulin Receptors 1 item
  277. IRG-1R 1 item
  278. Proton Pump 1 item
  279. cAMP 1 item
  280. Sulfonylurea receptors 1 item
  281. Cdc2-like kinase (Clk) 1 item
  282. eEF-2 1 item
  283. Inward Rectifier Potassium (Kir) Channels 3item
  284. Arp2/3 complex 1 item
  285. Cdc7 1 item
  286. CMV 1 item
  287. ZAP-70 1 item
  288. Catechol O-Methyltransferase (COMT) 2item
  289. fibrinolysis 1 item
  290. Angiotensin AT1 Receptors 1 item
  291. D4 Receptors 1 item
  292. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  293. NMDA receptor 1 item
  294. HBV Proteases 1 item
  295. Hydroxylases 2item
  296. Flk-1 1 item
  297. Papains 2item
  298. Protein Arginine Methyltransferases 1 item
  299. IMPDH 1 item
  300. Na /Ca2 Exchangers (NCXs) 1 item
  301. NAE 2item
  302. Ubiquitin-activating Enzyme E1 2item
  303. SUMOylation 1 item
  304. ATGL 1 item
  305. BACE 3item
  306. Cytidine deaminases 1 item
  307. angiogenesis 1 item
  308. Glucagon Receptors 1 item
  309. 15-PGDH 1 item
  310. DPP-4 5item
  311. c-RET 3item
  312. Nonstructural protein 5B (NS5B) 1 item
  313. p70 rsk 3item
  314. voltage-gated chloride channels 1 item
  315. FPTase 1 item
  316. Microtubule/Tubulin 1 item
  317. VEGFR3/FLT4 1 item
  318. NTRK1/TRKA 1 item
  319. CSF-1R/c-Fms 1 item
  320. Menin-MLL 2item
  321. Tryptophan hydroxylases (TPH) 2item
  322. ADAMs 1 item
  323. NMPRTase 1 item
  324. Bfl-1 1 item
  325. TAM kinase 1 item
  326. sodium channels 1 item
  327. p53-MDM2 interaction 2item
  328. nuclear export 1 item
  329. CRM1 1 item
  330. PTP 1 item
  331. KDR 2item
  332. Fyn kinase 1 item
  333. Abl kinases 1 item
  334. Trypsin-like protease 1 item
  335. AXL 1 item
  336. Glyoxalase I 1 item
  337. dCTP Pyrophosphatases 1 item
  338. Protein polybromo-1 1 item
  339. SMARCA4 1 item
  340. SMARCA2 1 item
  341. ERAD 1 item
  342. Dipeptidyl-peptidase II 1 item
  343. p53 4item
  344. metalloprotease 1 item
  345. HDAC 2item
  346. KDM 2item
  347. 5-HT receptors 1 item
  348. sodium channel 3item
  349. c-Fms tyrosine kinase 1 item
  350. human lyase 1 item
  351. insulin 1 item
  352. Ub-conjugating enzyme (E2) complex 1 item
  353. Smoothened receptor 1 item
  354. quinone oxidoreductase 1 item
  355. cysteine protease 2item
  356. Nrf2/ARE signal 1 item
  357. PPAR 1 item
  358. haspin kinase 1 item
  359. STK 1 item
  360. USP1/USF1 complex 1 item
  361. IKK 1 item
  362. MSK 1 item
  363. gp120-CD4 interaction 1 item
  364. HCV polymerase 3item
  365. Ftase 1 item
  366. Subtilisin/Kex2p-like proprotein convertase 1 item
  367. PC-PLC 2item
  368. Elastases 1 item
  369. P97 ATPase 1 item
  370. NTPDases 1 item
  371. Antibiotic 1 item
  372. Mer tyrosine kinase 1 item
  373. Hec1 1 item
  374. neprilysin 1 item
  375. GLI 1 item
  376. decarboxylase 1 item
  377. HMGCR 1 item
  378. AAT 1 item
  379. ErbB-2 1 item
  380. adrenergic receptor 2item
  381. 5-HT4 Receptor 1 item
  382. sterol demethylase 1 item
  383. PDK-1 1 item
  384. GAPDH 1 item
  385. telomerase 1 item
  386. Histone Acetyltransferases (HATs) 3item
  387. complex I of the mitochondrial electron transport chain 1 item
  388. F1 Fo-ATPase 1 item
  389. Prk 1 item
  390. potassium channel 1 item
  391. calcium channel 1 item
  392. Ribonucleotide Reductases 1 item
  393. Trx 1 item
  394. Tyrosinases 1 item
  395. HSP70 1 item
  396. ICAM 1 item
  397. ITK 1 item
  398. HIF-PH 1 item
  399. NOD1 1 item
  400. NUAK 1 item
  401. Rho 1 item
  402. Ubiquitin E3 Ligases 1 item
  403. DCLK2 1 item
  404. FAAH 1 item
  405. PTK 1 item
  406. integrase 1 item
  407. L3MBTL 1 item
  408. NOS 2item
  409. MDMX 1 item
  410. TYK2 2item
  411. MUSK 1 item
  412. MAP3K 1 item
  413. GPR3 1 item
  414. Lck 1 item
  415. Adenosine Deaminases 2item
  416. mitochondrial pyruvate carrier (MPC) 1 item
  417. Thrombin Receptor 1 item
  418. prolactin secretion 1 item
  419. gonadotropin release 1 item
  420. DprE 1 item
  421. carnitine reabsorption 1 item
  422. Histamine receptors 1 item
  423. GluR 1 item
  424. 5-HT receptor 1 item
  425. dopamine receptors 1 item
  426. AMPA receptor 1 item
  427. 5-alpha Reductases 1 item
  428. Flk1 2item
  429. p21 1 item
  430. DNA Ligases 1 item
  431. Prostaglandin synthesis 1 item
  432. Protein Tyrosine Phosphatases 1 item
  433. alkaline phosphatases 1 item
  434. ATPases 1 item
  435. glutamate release 1 item
  436. PAFR 1 item
  437. Aromatases 2item
  438. DHFR 1 item
  439. GARFT 1 item
  440. PHF 1 item
  441. FGR 1 item
  442. YES 2item
  443. Fyn 2item
  444. ARG 1 item
  445. Autotaxin 1 item
  446. UCH 1 item
  447. RHA 1 item
  448. HCV NS3-4A protease 1 item
  449. TRPC channel 1 item
  450. PKD 1 item
  451. Pyruvate kinases 1 item
  452. Thioredoxin Reductases 1 item
  453. enoyl-acyl-carrier protein reductase 1 item
  454. SHIP 1 item
  455. FKBP 1 item
  456. MCL1 1 item
  457. Bcl-w 1 item
  458. glutathione peroxidase 4 1 item
  459. NADH oxidase 1 item
  460. S-adenosylhomocysteine hydrolase 1 item
  461. Rho-kinase 1 item
  462. tropomyosin receptor kinase 1 item
  463. LSD 1 item
  464. DDX3 1 item
  465. PRMT 1 item
  466. ACE 1 item
  467. GLP 1 item
  468. SK 1 item
  469. MST 1 item
  470. PPK 1 item
  471. c-Syk 1 item
  472. CDK1/CyclinB 1 item
  473. NHE 1 item
  474. IDO 2item
  475. Tph 1 item
  476. PIM1 kinase 1 item
  477. phospholipase A2 1 item
  478. reverse transcriptase 1 item
  479. epoxide hydrolase 1 item
  480. Serotonin (5-HT) reuptake 1 item
  481. Cholesterol absorption 1 item
  482. Vascular Disrupting Agents (VDA) 1 item
  483. Androgen Receptor 1 item
  484. Substance P/NK1 Receptor 1 item
  485. gp120/CD4 1 item
  486. Histone Methyltransferase 1 item
  487. ATM 2item
  488. Sirtuin 1 item
  489. NE 1 item
  490. PIKfyve 1 item
  491. Bax 1 item
  492. Glycogen Phosphorylases 1 item
  493. RGS 1 item
  494. MTH1 1 item
  495. PTEN 1 item
  496. Insulin Receptor 1 item
  497. NS3/4a Proteases 1 item
  498. Ca2 -ATPases 1 item
  499. p90 S6K 1 item
  500. Dynamins 1 item
Reported Experiments
  1. Animal Experiments 964item
  2. Cell Experiments 786item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 2item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 6item
  7. Acute Myeloid Leukemia 26item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 11item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 120item
  19. Cancer 545item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 6item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 48item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 43item
  32. Depression 2item
  33. Diabetes 8item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 4item
  38. Erectile Dysfunction 4item
  39. Friedreich's Ataxia 2item
  40. Fungal Infection 1 item
  41. Fungi 1 item
  42. Glioblastoma 32item
  43. Glioma 18item
  44. HCV 5item
  45. Heart Failure 4item
  46. Hepatic Cancer 2item
  47. Hepatitis C 4item
  48. Hepatocellular Carcinoma 7item
  49. HIV 14item
  50. HIV Infections 10item
  51. Hypercholesterolemia 3item
  52. Immunological Diseases 1 item
  53. Inflammation 1 item
  54. Inflammatory Bowel Disease 1 item
  55. Inflammatory Diseases 16item
  56. Influenza 3item
  57. Kidney Injury Studies 2item
  58. Leukemia 27item
  59. Liver Cancer 3item
  60. Lung Cancer 44item
  61. Lung Carcinoma 4item
  62. Lymphoma 31item
  63. Mantle Cell Lymphoma 2item
  64. Medulloblastoma 1 item
  65. Melanoma 35item
  66. Mixed Lineage Leukemia 3item
  67. Multiple Myeloma 24item
  68. Myelofibrosis 2item
  69. Myeloma 6item
  70. Neuroblastoma 13item
  71. Neurocognitive Disorders 1 item
  72. Neuronal Protection 1 item
  73. Non-small Cell Lung Cancer 27item
  74. Non-small Cell Lung Carcinoma 2item
  75. Obsessive-Compulsive Disorder 1 item
  76. Osteoporosis 3item
  77. Ovarian Cancer 36item
  78. Pancreatic Cancer 49item
  79. Pancreatic Carcinoma 3item
  80. Prostate Cancer 55item
  81. Psoriasis 4item
  82. Psoriasis Vulgaris 1 item
  83. Pulmonary Arterial Hypertension 2item
  84. Pulmonary Fibrosis 2item
  85. Renal Cancer 4item
  86. Renal Cell Carcinoma 8item
  87. Rheumatoid Arthritis 14item
  88. Sarcoma 1 item
  89. Schizophrenia 8item
  90. Sleep Disorders 2item
  91. Soft Tissue Sarcoma 1 item
  92. Squamous Cell Carcinoma 2item
  93. Testicular Cancer 2item
  94. Thyroid Cancer 6item
  95. Tuberculosis 1 item
  96. Type 2 Diabetes 12item