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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

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  1. Gefitinib hydrochloride
    A3433 Gefitinib hydrochloride
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; ≥4.28 mg/mL
  2. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  3. AG-490
    A4139 AG-490
     3 Citation
    Target: EGFR|JAK
    Summary: JAK2/EGFR inhibitor
      insoluble in H2O; ≥14.7 mg/mL
  4. WHI-P154
    A4150 WHI-P154
    Target: VEGFR|Src|EGFR|JAK
    Summary: JAK3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥125.6 mg/mL
  5. PP 1
    A8215 PP 1
    Target: Src|EGFR|JAK|ZAP-70
    Summary: Src family tyrosine kinase inhibitor
  6. AZ5104
    B5836 AZ5104
    Target: EGFR
    Summary: EGFR inhibitor
      insoluble in H2O; ≥16.95 mg/mL
  7. WZ8040
    A1393 WZ8040
    Target: EGFR
    Summary: EGFR T790M inhibitor,irreversible amd potent
      ≥24.05 mg/mL
  8. PD168393
    A2024 PD168393
    Target: PDGFR|FGFR|EGFR|PKC|insulin
    Summary: EGFR inhibitor
  9. AZD-9291
    B1104 AZD-9291
     1 Citation
    Target: EGFR
    Summary: Mutated forms EGFR inhibitor
      ≥24.98 mg/mL
  10. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL

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