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Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

A3009 Sorafenib

2 Citation

Target: Raf|VEGFR

Summary: Raf kinases and tyrosine kinases inhibitor

≥23.25 mg/mL
A8252 Nintedanib (BIBF 1120)

3 Citation

Target: VEGFR|PDGFR|FGFR

Summary: VEGFR/PDGFR/FGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
B2172 PP121

Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck

Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
A3954 ZM323881

Target: VEGFR

Summary: VEGFR-2/KDR inhibitor,potent and selective

Soluble in DMSO
A8683 NVP-BHG712

Target: Eph Receptors|VEGFR

Summary: EphB4 inhibitor,potent and selective

≥25.15 mg/mL
A2412 CP-724714

Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R

Summary: HER2 inhibitor,potent and selective

≥23.5 mg/mL
A3632 Motesanib

Target: VEGFR

Summary: Inhibitor of Flk-1/Flt-4/PDGFR-/c-Kit

≥42 mg/mL
A2168 Dovitinib (TKI-258, CHIR-258)

2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
B5832 Altiratinib

1 Citation

Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2

Summary: c-MET/TIE-2/VEGFR inhibitor

≥21.55 mg/mL
A5057 MGCD-265

Target: VEGFR|c-MET

Summary: Met/Flt/Flk/Ron/Tie-2 inhibitor

≥25.9 mg/mL