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  • Search results for: 'research area pi3k akt signaling s6 kinase'

Search results for: 'research area pi3k akt signaling s6 kinase'

Items 61-70 of 289

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  1. BMS-754807
    A1185 BMS-754807
    Target: Insulin and Insulin-like Receptors
    Summary: IGF-1R/InsR inhibitor,potent and selective
      ≥23.05 mg/mL
  2. PF-562271 HCl
    A8345 PF-562271 HCl
    Target: FAK|Pyk2
    Summary: FAK/Pyk2 inhibitor
      ≥26.35 mg/mL
  3. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL
  4. Trametinib (GSK1120212)
    A3018 Trametinib (GSK1120212)
     7 Citation
    Target: MEK
    Summary: MEK1 and MEK2 inhibitor, potent and selective
      insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
  5. R788 disodium
    A8332 R788 disodium
    Target: Syk
    Summary: Syk inhibitor,ATP competitive and potent
      ≥62.4 mg/mL
  6. LY2584702
    B5815 LY2584702
    Target: p70 rsk
    Summary: p70 S6 kinase inhibitor
      ≥22.25 mg/mL
  7. PF-03814735
    A4128 PF-03814735
    Target: Aurora Kinases
    Summary: Aurora A/B inhibitor
      Soluble in DMSO
  8. MLN8054
    A4114 MLN8054
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
  9. Fenretinide
    A3412 Fenretinide
    Target: FAK
    Summary: Synthetic retinoid agonist
      insoluble in H2O; ≥19.6 mg/mL
  10. CP-466722
    A8625 CP-466722
    Target: ATM
    Summary: ATM inhibitor,potent and reversible
      ≥4.36 mg/mL

Items 61-70 of 289

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Proteases 2item
  2. Apoptosis 3item
  3. Chromatin/Epigenetics 25item
  4. Metabolism 3item
  5. MAPK Signaling 28item
  6. Tyrosine Kinase 87item
  7. DNA Damage/DNA Repair 10item
  8. PI3K/Akt/mTOR Signaling 51item
  9. Cell Cycle/Checkpoint 54item
  10. Ubiquitination/ Proteasome 3item
  11. JAK/STAT Signaling 25item
  12. TGF-β / Smad Signaling 29item
  13. Angiogenesis 1 item
  14. GPCR/G protein 2item
  15. Stem Cell 15item
  16. Membrane Transporter/Ion Channel 4item
  17. Endocrinology and Hormones 1 item
  18. Neuroscience 3item
  19. Obesity, Appetite Control & Diabetes 2item
  20. Other Signal Transduction 2item
  21. Others 14item
  22. Immunology/Inflammation 2item
  23. Cardiovascular 1 item
Reversibility
  1. Reversible 22item
  2. Irreversible 5item
Target
  1. Cyclin-Dependent Kinases 21item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 5item
  4. PI3K 22item
  5. Raf 8item
  6. Aurora Kinases 13item
  7. CSF-1R 2item
  8. mTOR 11item
  9. Androgen Receptors 1 item
  10. FLT3 8item
  11. GSK-3 8item
  12. P-glycoprotein (P-gp) 1 item
  13. PLK 4item
  14. Chk 5item
  15. Eph Receptors 3item
  16. VEGFR 19item
  17. PDGFR 14item
  18. c-Kit 6item
  19. RET 3item
  20. IRAK 2item
  21. Bromodomain-containing proteins(BRDs) 1 item
  22. Phosphodiesterases (PDEs) 1 item
  23. p38 7item
  24. PKB 1 item
  25. JNK 4item
  26. SGK 2item
  27. Bcr-Abl 10item
  28. MEK 8item
  29. PORCN 1 item
  30. FGFR 6item
  31. Pim 4item
  32. GABAB Receptors 1 item
  33. Smoothened 1 item
  34. Ribosomal s6 kinases (RSK) 1 item
  35. MET 5item
  36. Src 8item
  37. Trk Receptors 2item
  38. STAT 4item
  39. EGFR 11item
  40. Hedgehog 1 item
  41. ROCK 6item
  42. BTK 1 item
  43. PAK 3item
  44. FAK 4item
  45. BMP and Other Activin Receptors 3item
  46. JAK 9item
  47. Syk 5item
  48. DNA-PK 5item
  49. HSP90 1 item
  50. AMPK 2item
  51. PDHK 1 item
  52. TNKS 1 item
  53. ErbB 2item
  54. S6 kinases 1 item
  55. Toll-like receptors (TLRs) 1 item
  56. Adenosine Kinases 2item
  57. ERK 3item
  58. c-MET 5item
  59. PKC 5item
  60. Ubiquitin-specific proteases 1 item
  61. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  62. Lyn 1 item
  63. HER2 2item
  64. Pyk2 3item
  65. LRRK2 3item
  66. Insulin and Insulin-like Receptors 2item
  67. Melanocortin (MC) Receptors 1 item
  68. ALK 3item
  69. ROS1 1 item
  70. Sphingosine kinases (SphKs) 1 item
  71. PKG 1 item
  72. PKA 1 item
  73. Myosin light chain kinases (MLCKs) 2item
  74. CaM-KK 1 item
  75. MELK 1 item
  76. Insulin-like growth factors (IGFs) 1 item
  77. Clk 1 item
  78. NUAK1 1 item
  79. NUAK2 1 item
  80. MK2 2item
  81. Fatty-acid-binding proteins (FABPs) 1 item
  82. Tie-2 2item
  83. RSK 1 item
  84. ATM/ATR 3item
  85. CK1 1 item
  86. Farnesyl Diphosphate Synthases 1 item
  87. CK2 3item
  88. HIPK2 1 item
  89. HIPK3 1 item
  90. P2X Receptors 1 item
  91. c-Fyn 1 item
  92. TAK1 1 item
  93. P110 1 item
  94. Hck 1 item
  95. NO Donors / Precursors 1 item
  96. IL Receptors 1 item
  97. Insulin Receptors 1 item
  98. IRG-1R 1 item
  99. eEF-2 1 item
  100. Cdc7 1 item
  101. ZAP-70 1 item
  102. c-RET 1 item
  103. p70 rsk 1 item
  104. TAM kinase 1 item
  105. AXL 1 item
  106. c-Fms tyrosine kinase 1 item
  107. STK 1 item
  108. MSK 1 item
  109. Lyn kinase 1 item
  110. ITK 1 item
  111. NUAK 1 item
  112. DCLK2 1 item
  113. Lck 1 item
  114. PKD 1 item
  115. tropomyosin receptor kinase 1 item
  116. SK 1 item
  117. ATM 2item
  118. PIKfyve 1 item
  119. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 253item
  2. Cell Experiments 158item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 17item
  3. Adrenocortical Carcinoma 2item
  4. Advanced Renal Cell Carcinoma 1 item
  5. Bladder Cancer 5item
  6. Bladder Carcinoma 1 item
  7. B-lymphoid Malignancies 1 item
  8. Breast Cancer 55item
  9. Cancer 186item
  10. Cervical Cancer 4item
  11. Cholangiocarcinoma 2item
  12. Chronic Lymphocytic Leukemia 2item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 23item
  15. Colon Carcinoma 3item
  16. Colorectal Cancer 24item
  17. Glioblastoma 21item
  18. Glioma 9item
  19. Hepatocellular Carcinoma 4item
  20. HIV Infections 1 item
  21. Immunological Diseases 1 item
  22. Inflammatory Bowel Disease 1 item
  23. Inflammatory Diseases 4item
  24. Leukemia 9item
  25. Liver Cancer 3item
  26. Lung Cancer 19item
  27. Lung Carcinoma 3item
  28. Lymphoma 10item
  29. Mantle Cell Lymphoma 1 item
  30. Melanoma 12item
  31. Multiple Myeloma 6item
  32. Myelofibrosis 1 item
  33. Myeloma 2item
  34. Neuroblastoma 4item
  35. Non-small Cell Lung Cancer 8item
  36. Non-small Cell Lung Carcinoma 1 item
  37. Ovarian Cancer 18item
  38. Pancreatic Cancer 27item
  39. Pancreatic Carcinoma 2item
  40. Prostate Cancer 22item
  41. Psoriasis 1 item
  42. Pulmonary Arterial Hypertension 1 item
  43. Pulmonary Fibrosis 1 item
  44. Renal Cancer 3item
  45. Renal Cell Carcinoma 5item
  46. Rheumatoid Arthritis 6item
  47. Thyroid Cancer 5item
  48. Type 2 Diabetes 3item