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  • Search results for: 'research area pi3k akt signaling s6 kinase'

Search results for: 'research area pi3k akt signaling s6 kinase'

Items 91-100 of 107

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  1. AZD-9291
    B1104 AZD-9291
     1 Citation
    Target: EGFR
    Summary: Mutated forms EGFR inhibitor
      ≥24.98 mg/mL
  2. G-749
    A8889 G-749
    Target: Aurora Kinases|FLT3|c-RET
    Summary: FLT3 inhibitor
      ≥26.05 mg/mL
  3. BAY 61-3606
    A3227 BAY 61-3606
    Target: Syk
    Summary: Syk Inhibitor
      insoluble in H2O; insoluble in EtOH; ≥7.94 mg/mL
  4. LOXO-101
    B6176 LOXO-101
    Target: tropomyosin receptor kinase
    Summary: tropomyosin receptor kinases (TRK) inhibitor
      ≥18.47 mg/mL
  5. HG-10-102-01
    B1262 HG-10-102-01
     1 Citation
    Target: LRRK2
    Summary: LRRK2 inhibitor
      insoluble in H2O; ≥18.9 mg/mL
  6. BMS-509744
    A3250 BMS-509744
    Target: ITK
    Summary: Itk inhibitor,potent and selective
      Soluble in DMSO
  7. MGCD-265
    A5057 MGCD-265
    Target: VEGFR|c-MET
    Summary: Met/Flt/Flk/Ron/Tie-2 inhibitor
      ≥25.9 mg/mL
  8. Ki8751
    A1821 Ki8751
    Target: VEGFR
    Summary: VEGFR-2 inhibitor,potent and selective
      ≥23.45 mg/mL
  9. GNE0877
    B4633 GNE0877
    Target: LRRK2
    Summary: Potent and selective LRRK2 inhibitor
      ≥21 mg/mL
  10. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL

Items 91-100 of 107

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  1. Category Tyrosine Kinase Remove This Item
  2. Reported Experiments Animal Experiments Remove This Item
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Category
  1. Bcr-Abl 6item
  2. Axl 5item
  3. ALK 9item
  4. c-FMS 1 item
  5. c-Kit 3item
  6. c-MET 9item
  7. c-RET 3item
  8. CSF-1R 2item
  9. EGFR 17item
  10. FAK 3item
  11. FGFR 8item
  12. FLT3 7item
  13. HER2 8item
  14. IGF1R 3item
  15. IRAK 1 item
  16. ITK 1 item
  17. LRRK2 4item
  18. PDGFR 10item
  19. Pyk2 2item
  20. Spleen Tyrosine Kinase (Syk) 5item
  21. Src 7item
  22. Tie-2 2item
  23. Trk 2item
  24. VEGFR 23item
Specificity
  1. Selective 80item
Reversibility
  1. Reversible 8item
  2. Irreversible 5item
Target
  1. Histone Deacetylases (HDACs) 1 item
  2. Raf 5item
  3. Aurora Kinases 3item
  4. CSF-1R 4item
  5. FLT3 7item
  6. Eph Receptors 1 item
  7. VEGFR 27item
  8. PDGFR 18item
  9. c-Kit 11item
  10. RET 3item
  11. IRAK 1 item
  12. Bcr-Abl 8item
  13. FGFR 11item
  14. MET 5item
  15. Src 9item
  16. Trk Receptors 2item
  17. STAT 1 item
  18. EGFR 16item
  19. FAK 3item
  20. BMP and Other Activin Receptors 2item
  21. JAK 2item
  22. Syk 5item
  23. ErbB 4item
  24. c-MET 5item
  25. PKC 1 item
  26. Lyn 2item
  27. HER2 2item
  28. Pyk2 3item
  29. LRRK2 4item
  30. Insulin and Insulin-like Receptors 3item
  31. ALK 5item
  32. ROS1 1 item
  33. Insulin-like growth factors (IGFs) 1 item
  34. Angiotensin-Converting Enzymes (ACEs) 1 item
  35. Tie-2 1 item
  36. 5-Lipoxygenases 1 item
  37. Insulin Receptors 1 item
  38. IRG-1R 1 item
  39. ZAP-70 1 item
  40. c-RET 2item
  41. TAM kinase 1 item
  42. Fyn kinase 1 item
  43. AXL 1 item
  44. c-Fms tyrosine kinase 1 item
  45. insulin 1 item
  46. Lyn kinase 1 item
  47. Mer tyrosine kinase 1 item
  48. ErbB-2 1 item
  49. ITK 1 item
  50. DCLK2 1 item
  51. PTK 1 item
  52. Flk1 1 item
  53. YES 1 item
  54. Fyn 1 item
  55. enoyl-acyl-carrier protein reductase 1 item
  56. tropomyosin receptor kinase 1 item
  57. Insulin Receptor 1 item
Related Disease
  1. Acute Myeloid Leukemia 5item
  2. Adrenocortical Carcinoma 1 item
  3. Advanced Renal Cell Carcinoma 1 item
  4. Bladder Cancer 4item
  5. Bladder Carcinoma 1 item
  6. Breast Cancer 19item
  7. Cancer 78item
  8. Cervical Cancer 1 item
  9. Cholangiocarcinoma 1 item
  10. Clear Cell Renal Cell Carcinoma 1 item
  11. Colon Cancer 2item
  12. Colon Carcinoma 1 item
  13. Colorectal Cancer 11item
  14. Glioblastoma 6item
  15. Glioma 3item
  16. Hepatocellular Carcinoma 3item
  17. Leukemia 3item
  18. Liver Cancer 2item
  19. Lung Cancer 6item
  20. Lung Carcinoma 3item
  21. Lymphoma 5item
  22. Melanoma 2item
  23. Multiple Myeloma 3item
  24. Neuroblastoma 1 item
  25. Non-small Cell Lung Cancer 4item
  26. Ovarian Cancer 6item
  27. Pancreatic Cancer 10item
  28. Prostate Cancer 8item
  29. Pulmonary Arterial Hypertension 1 item
  30. Renal Cancer 2item
  31. Renal Cell Carcinoma 4item
  32. Rheumatoid Arthritis 2item
  33. Thyroid Cancer 3item