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  • Search results for: 'research area pi3k akt signaling s6 kinase'

Search results for: 'research area pi3k akt signaling s6 kinase'

Items 81-90 of 226

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  1. Nintedanib (BIBF 1120)
    A8252 Nintedanib (BIBF 1120)
     3 Citation
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
  2. TAE684 (NVP-TAE684)
    A8251 TAE684 (NVP-TAE684)
    Summary: ALK inhibitor,potent and selective
      ≥61.4 mg/mL
  3. SGX-523
    A1196 SGX-523
     1 Citation
    Target: MET
    Summary: MET inibitor, highly selective, ATP-competitive
      ≥17.95 mg/mL
  4. Brivanib (BMS-540215)
    A2597 Brivanib (BMS-540215)
    Target: VEGFR|FGFR|Flk1
    Summary: VEGFR-2 inhibitor,ATP-competitive
      insoluble in H2O; ≥18.5 mg/mL
  5. Lenvatinib (E7080)
    A2174 Lenvatinib (E7080)
    Target: VEGFR|PDGFR|RET
    Summary: VEGFR inhibitor
      ≥21.35 mg/mL
  6. GSK1904529A
    A1302 GSK1904529A
    Target: Insulin and Insulin-like Receptors
    Summary: Selective IGF-1R/IR inhibitor
      ≥42.6 mg/mL
  7. Quizartinib (AC220)
    A5793 Quizartinib (AC220)
    Target: FLT3
    Summary: FLT3 inhibitor,potent and selective
      ≥28.03 mg/mL
  8. Crenolanib (CP-868596)
    A8307 Crenolanib (CP-868596)
     1 Citation
    Target: FLT3|PDGFR
    Summary: PDGFR-β inhibitor,potent and selective
      ≥22.2 mg/mL
  9. Tivantinib (ARQ 197)
    A8325 Tivantinib (ARQ 197)
     2 Citation
    Target: MET
    Summary: C-Met inhibitor,non-ATP-competitive
      ≥18.47 mg/mL
  10. R428
    A8329 R428
     10 Citation
    Summary: Selective Axl inhibitor
      ≥25 mg/mL

Items 81-90 of 226

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  1. Category Tyrosine Kinase Remove This Item
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Category
  1. Bcr-Abl 14item
  2. Ack1 1 item
  3. Axl 6item
  4. ALK 18item
  5. BMX Kinase 1 item
  6. Broad Spectrum Protein Kinase Inhibitor 9item
  7. c-FMS 2item
  8. c-Kit 5item
  9. c-MET 10item
  10. c-RET 6item
  11. CSF-1R 2item
  12. DDR1/DDR2 Receptor 1 item
  13. EGFR 47item
  14. EphB4 1 item
  15. FAK 6item
  16. FGFR 13item
  17. FLT3 14item
  18. HER2 11item
  19. IGF1R 6item
  20. Insulin Receptor 2item
  21. IRAK 3item
  22. ITK 1 item
  23. LRRK2 4item
  24. PDGFR 17item
  25. PTKs/RTKs 2item
  26. Pyk2 2item
  27. Spleen Tyrosine Kinase (Syk) 9item
  28. Src 19item
  29. Tie-2 2item
  30. Trk 4item
  31. VEGFR 35item
Specificity
  1. Selective 87item
Reversibility
  1. Reversible 8item
  2. Irreversible 5item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. Raf 5item
  4. Aurora Kinases 3item
  5. CSF-1R 4item
  6. FLT3 7item
  7. Eph Receptors 2item
  8. VEGFR 27item
  9. PDGFR 18item
  10. c-Kit 11item
  11. RET 3item
  12. IRAK 3item
  13. Bcr-Abl 10item
  14. FGFR 11item
  15. MET 5item
  16. Src 11item
  17. Trk Receptors 2item
  18. STAT 1 item
  19. EGFR 18item
  20. FAK 3item
  21. BMP and Other Activin Receptors 2item
  22. JAK 2item
  23. Syk 5item
  24. ErbB 4item
  25. Kinases 1 item
  26. c-MET 5item
  27. PKC 2item
  28. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  29. Lyn 2item
  30. HER2 2item
  31. Pyk2 3item
  32. LRRK2 4item
  33. Insulin and Insulin-like Receptors 3item
  34. ALK 5item
  35. ROS1 1 item
  36. PKG 1 item
  37. PKA 1 item
  38. Myosin light chain kinases (MLCKs) 1 item
  39. Insulin-like growth factors (IGFs) 1 item
  40. Angiotensin-Converting Enzymes (ACEs) 1 item
  41. Tie-2 1 item
  42. c-Fyn 1 item
  43. 5-Lipoxygenases 1 item
  44. Insulin Receptors 1 item
  45. IRG-1R 1 item
  46. ZAP-70 1 item
  47. c-RET 2item
  48. TAM kinase 1 item
  49. Fyn kinase 1 item
  50. Abl kinases 1 item
  51. AXL 1 item
  52. c-Fms tyrosine kinase 1 item
  53. insulin 1 item
  54. Lyn kinase 1 item
  55. Mer tyrosine kinase 1 item
  56. ErbB-2 1 item
  57. ITK 1 item
  58. DCLK2 1 item
  59. PTK 1 item
  60. Flk1 1 item
  61. YES 1 item
  62. Fyn 1 item
  63. enoyl-acyl-carrier protein reductase 1 item
  64. tropomyosin receptor kinase 1 item
  65. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 107item
  2. Cell Experiments 77item
Related Disease
  1. Acute Myeloid Leukemia 5item
  2. Adrenocortical Carcinoma 1 item
  3. Advanced Renal Cell Carcinoma 1 item
  4. Bladder Cancer 4item
  5. Bladder Carcinoma 1 item
  6. Breast Cancer 19item
  7. Cancer 81item
  8. Cervical Cancer 1 item
  9. Cholangiocarcinoma 1 item
  10. Clear Cell Renal Cell Carcinoma 1 item
  11. Colon Cancer 2item
  12. Colon Carcinoma 1 item
  13. Colorectal Cancer 11item
  14. Glioblastoma 6item
  15. Glioma 3item
  16. Hepatocellular Carcinoma 3item
  17. Leukemia 3item
  18. Liver Cancer 2item
  19. Lung Cancer 7item
  20. Lung Carcinoma 3item
  21. Lymphoma 5item
  22. Melanoma 3item
  23. Multiple Myeloma 3item
  24. Neuroblastoma 1 item
  25. Non-small Cell Lung Cancer 4item
  26. Ovarian Cancer 6item
  27. Pancreatic Cancer 10item
  28. Prostate Cancer 8item
  29. Pulmonary Arterial Hypertension 1 item
  30. Renal Cancer 2item
  31. Renal Cell Carcinoma 4item
  32. Rheumatoid Arthritis 2item
  33. Thyroid Cancer 3item