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  • Search results for: 'research area pi3k akt signaling s6 kinase'

Search results for: 'research area pi3k akt signaling s6 kinase'

Items 121-130 of 240

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  1. ENMD-2076
    A4130 ENMD-2076
    Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms
    Summary: Selective Aurora A/Flt3 inhibitor
      insoluble in H2O; ≥18.75 mg/mL
  2. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      insoluble in H2O; ≥18.55 mg/mL
  3. 3-Methyladenine
    A8353 3-Methyladenine
     3 Citation
    Target: PI3K
    Summary: Class III PI3K inhibitor
      ≥5 mg/mL
  4. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  5. (-)-Epigallocatechin gallate (EGCG)
    A2600 (-)-Epigallocatechin gallate (EGCG)
    Target: BACE
    Summary: Antioxidant, antiangiogenic and antitumor agent
      ≥22.9 mg/mL
  6. Lapatinib Ditosylate
    A3967 Lapatinib Ditosylate
    Target: EGFR|ErbB-2
    Summary: EGFR/HER2 inhibitor,potent and selective
      ≥24.3 mg/mL
  7. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  8. Dacomitinib (PF299804, PF299)
    A8319 Dacomitinib (PF299804, PF299)
    Target: ErbB
    Summary: HER inhibitor
      ≥23.5 mg/mL
  9. CUDC-101
    A4092 CUDC-101
     1 Citation
    Target: Histone Deacetylases (HDACs)|EGFR|ErbB
    Summary: Multitargeted HDAC inhibitor
      ≥21.7 mg/mL
  10. PF-4708671
    B2228 PF-4708671
     1 Citation
    Target: p70 rsk
    Summary: P70 S6K1 isoform inhibitor,cell-permeable
      ≥37.8 mg/mL

Items 121-130 of 240

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Category
  1. Natural Products 1 item
Specificity
  1. Selective 186item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 19item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 2item
  3. Akt 10item
  4. PI3K 22item
  5. Raf 10item
  6. Aurora Kinases 16item
  7. CSF-1R 4item
  8. mTOR 12item
  9. Androgen Receptors 1 item
  10. FLT3 7item
  11. GSK-3 5item
  12. P-glycoprotein (P-gp) 1 item
  13. PLK 5item
  14. Chk 4item
  15. Eph Receptors 3item
  16. VEGFR 27item
  17. PDGFR 17item
  18. c-Kit 9item
  19. RET 4item
  20. Bromodomain-containing proteins(BRDs) 1 item
  21. Phosphodiesterases (PDEs) 1 item
  22. p38 3item
  23. JNK 1 item
  24. SGK 2item
  25. Bcr-Abl 6item
  26. MEK 5item
  27. PORCN 1 item
  28. FGFR 9item
  29. Pim 3item
  30. Smoothened 1 item
  31. Ribosomal s6 kinases (RSK) 1 item
  32. MET 5item
  33. Src 8item
  34. Trk Receptors 1 item
  35. STAT 5item
  36. EGFR 14item
  37. Hedgehog 1 item
  38. PAK 3item
  39. FAK 4item
  40. BMP and Other Activin Receptors 2item
  41. JAK 8item
  42. Syk 3item
  43. DNA-PK 5item
  44. HSP90 1 item
  45. TNKS 1 item
  46. ErbB 4item
  47. ERK 3item
  48. c-MET 5item
  49. PKC 8item
  50. Ubiquitin-specific proteases 1 item
  51. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  52. Lyn 1 item
  53. HER2 1 item
  54. Pyk2 3item
  55. Insulin and Insulin-like Receptors 2item
  56. ALK 5item
  57. ROS1 1 item
  58. Sphingosine kinases (SphKs) 1 item
  59. PKG 2item
  60. PKA 5item
  61. Myosin light chain kinases (MLCKs) 1 item
  62. MELK 1 item
  63. Insulin-like growth factors (IGFs) 1 item
  64. MK2 1 item
  65. Tie-2 1 item
  66. RSK 1 item
  67. ATM/ATR 3item
  68. CK1 1 item
  69. Farnesyl Diphosphate Synthases 1 item
  70. CK2 1 item
  71. HIPK2 1 item
  72. HIPK3 1 item
  73. P110 1 item
  74. Hck 1 item
  75. MNK 1 item
  76. Insulin Receptors 1 item
  77. IRG-1R 1 item
  78. eEF-2 1 item
  79. Cdc7 1 item
  80. ZAP-70 1 item
  81. BACE 1 item
  82. c-RET 2item
  83. p70 rsk 2item
  84. VEGFR3/FLT4 1 item
  85. NTRK1/TRKA 1 item
  86. CSF-1R/c-Fms 1 item
  87. TAM kinase 1 item
  88. KDR 1 item
  89. AXL 1 item
  90. insulin 1 item
  91. Smoothened receptor 1 item
  92. Antibiotic 1 item
  93. ErbB-2 1 item
  94. PDK-1 1 item
  95. Prk 1 item
  96. Flk1 2item
  97. tropomyosin receptor kinase 1 item
  98. SK 1 item
  99. PPK 1 item
  100. c-Syk 1 item
  101. CDK1/CyclinB 1 item
  102. PIM1 kinase 1 item
  103. phospholipase A2 1 item
Reported Experiments
  1. Animal Experiments 227item
  2. Cell Experiments 152item