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  • Search results for: 'research area stem cell stem gsk 3'

Search results for: 'research area stem cell stem gsk 3'

Items 1-10 of 219

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  1. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.27 mg/mL
  2. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL
  3. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
  4. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  5. XAV-939
    A1877 XAV-939
     1 Citation
    Target: TNKS
    Summary: Tankyrase 1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.62 mg/mL
  6. GANT61
    A1615 GANT61
     1 Citation
    Target: GLI
    Summary: GLI antagonist
  7. Cyclopamine
    A8340 Cyclopamine
     1 Citation
    Target: Smoothened
    Summary: Hedgehog (Hh) signaling Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
  8. LY2940680
    A8651 LY2940680
    Target: Smoothened receptor
    Summary: Hedgehog/SMO antagonist,inhibits Hh signaling
  9. 3-Methyladenine
    A8353 3-Methyladenine
     3 Citation
    Target: PI3K
    Summary: Class III PI3K inhibitor
      ≥5 mg/mL
  10. FH535
    A3413 FH535
    Summary: Wnt/B-catenin inhibitor
      ≥36.1 mg/mL

Items 1-10 of 219

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  1. Category Signaling Pathways Remove This Item
  2. Reported Experiments Animal Experiments Remove This Item
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  1. Proteases 10item
  2. Apoptosis 24item
  3. Chromatin/Epigenetics 32item
  4. Metabolism 5item
  5. MAPK Signaling 9item
  6. Tyrosine Kinase 39item
  7. DNA Damage/DNA Repair 27item
  8. PI3K/Akt/mTOR Signaling 25item
  9. Microbiology & Virology 1 item
  10. Cell Cycle/Checkpoint 43item
  11. Ubiquitination/ Proteasome 10item
  12. JAK/STAT Signaling 15item
  13. TGF-β / Smad Signaling 4item
  14. Angiogenesis 1 item
  15. GPCR/G protein 4item
  16. Stem Cell 17item
  17. Membrane Transporter/Ion Channel 3item
  18. Endocrinology and Hormones 2item
  19. Neuroscience 3item
  20. Others 7item
  21. Immunology/Inflammation 1 item
Specificity
  1. Selective 161item
Reversibility
  1. Reversible 13item
  2. Irreversible 3item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 17item
  3. Proteasome 3item
  4. Histone Deacetylases (HDACs) 9item
  5. Inhibitor of apoptosis proteins (IAP) 2item
  6. Akt 7item
  7. Bcl-2 3item
  8. PI3K 12item
  9. Raf 4item
  10. Aurora Kinases 10item
  11. CSF-1R 1 item
  12. Glycoproteins 1 item
  13. MDM2 2item
  14. EZH2 2item
  15. mTOR 3item
  16. AP-1 1 item
  17. MMP 1 item
  18. DT-diaphorases 1 item
  19. FLT3 7item
  20. GSK-3 5item
  21. LPA Receptors 1 item
  22. P-glycoprotein (P-gp) 5item
  23. PLK 7item
  24. Chk 3item
  25. VEGFR 22item
  26. PDGFR 13item
  27. c-Kit 7item
  28. RET 2item
  29. Bromodomain-containing proteins(BRDs) 1 item
  30. Mcl-1 2item
  31. p38 1 item
  32. JNK 1 item
  33. SGK 1 item
  34. Bcr-Abl 2item
  35. MEK 5item
  36. PORCN 1 item
  37. DOT1L 1 item
  38. FGFR 7item
  39. Nrf2 1 item
  40. Deubiquitinating enzymes (DUBs) 1 item
  41. PP1 1 item
  42. PP2A 1 item
  43. Smoothened 3item
  44. MET 2item
  45. Src 3item
  46. Trk Receptors 2item
  47. STAT 3item
  48. Microtubules/Tubulins 4item
  49. Estrogen and Related Receptors 1 item
  50. EGFR 8item
  51. Hedgehog 1 item
  52. ROCK 1 item
  53. PAK 1 item
  54. JAK 6item
  55. p300 1 item
  56. Progesterone Receptors 1 item
  57. DNA-PK 2item
  58. HSP90 3item
  59. AMPK 1 item
  60. TNKS 1 item
  61. Topoisomerases 3item
  62. ErbB 2item
  63. DNA Methyltransferases 1 item
  64. ERK 2item
  65. c-MET 2item
  66. BMI-1 1 item
  67. PKC 5item
  68. Lyn 1 item
  69. SGLT 1 item
  70. RAD51 1 item
  71. HER2 1 item
  72. PARP 1 item
  73. ALK 3item
  74. Sphingosine kinases (SphKs) 1 item
  75. PKG 1 item
  76. PKA 4item
  77. Insulin-like growth factors (IGFs) 1 item
  78. CSF1R 1 item
  79. MK2 1 item
  80. 5-HT3 Receptors 1 item
  81. RSK 1 item
  82. Autophagy 2item
  83. ATM/ATR 2item
  84. Farnesyl Diphosphate Synthases 1 item
  85. Ron 1 item
  86. MAGL 1 item
  87. Histamine H2 Receptors 1 item
  88. MNK 1 item
  89. Glucocorticoid Receptors 1 item
  90. Insulin Receptors 1 item
  91. IRG-1R 1 item
  92. Cdc7 1 item
  93. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  94. NAE 1 item
  95. Ubiquitin-activating Enzyme E1 1 item
  96. SUMOylation 1 item
  97. PP4 1 item
  98. c-RET 2item
  99. p70 rsk 2item
  100. Microtubule/Tubulin 1 item
  101. Bfl-1 1 item
  102. p53-MDM2 interaction 1 item
  103. KDR 1 item
  104. p53 2item
  105. human lyase 1 item
  106. insulin 1 item
  107. Ub-conjugating enzyme (E2) complex 1 item
  108. Smoothened receptor 1 item
  109. HDM2 ubiquitin ligase 1 item
  110. Antibiotic 1 item
  111. DNA Alkylating 1 item
  112. GLI 1 item
  113. PDK-1 1 item
  114. Prk 1 item
  115. Ribonucleotide Reductases 1 item
  116. TYK2 1 item
  117. MUSK 1 item
  118. MAP3K 1 item
  119. Flk1 1 item
  120. RHA 1 item
  121. Bcl-w 1 item
  122. PPK 1 item
  123. c-Syk 1 item
  124. CDK1/CyclinB 1 item
  125. PIM1 kinase 1 item
  126. phospholipase A2 1 item
  127. Substance P/NK1 Receptor 1 item
  128. Bax 1 item