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  • Search results for: 'research area stem cell stem gsk 3'

Search results for: 'research area stem cell stem gsk 3'

Items 1-10 of 292

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  1. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.27 mg/mL
  2. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL
  3. 3-Deazaneplanocin,DZNep
    A1905 3-Deazaneplanocin,DZNep
     6 Citation
    Target: Hydrolase
    Summary: S-adenosylhomocysteine and EZH2 inhibitor
      insoluble in EtOH; ≥17.07 mg/mL
  4. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
  5. CHIR-99021 (CT99021) HCl
    A8396 CHIR-99021 (CT99021) HCl
    Target: GSK-3
    Summary: GSK-3α/β inhibitor
      ≥25.1 mg/mL
  6. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  7. XAV-939
    A1877 XAV-939
     1 Citation
    Target: TNKS
    Summary: Tankyrase 1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.62 mg/mL
  8. GSK 4112
    B7460 GSK 4112
    Target: Rev-Erb Receptors
    Summary: Rev-Erbα agonist
      insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
  9. Cyclopamine
    A8340 Cyclopamine
     1 Citation
    Target: Smoothened
    Summary: Hedgehog (Hh) signaling Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
  10. 3-Methyladenine
    A8353 3-Methyladenine
     3 Citation
    Target: PI3K
    Summary: Class III PI3K inhibitor
      ≥5 mg/mL

Items 1-10 of 292

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Category
  1. Proteases 19item
  2. Apoptosis 22item
  3. Chromatin/Epigenetics 33item
  4. Metabolism 17item
  5. MAPK Signaling 14item
  6. Tyrosine Kinase 35item
  7. DNA Damage/DNA Repair 28item
  8. PI3K/Akt/mTOR Signaling 28item
  9. Microbiology & Virology 8item
  10. Cell Cycle/Checkpoint 37item
  11. Ubiquitination/ Proteasome 12item
  12. JAK/STAT Signaling 11item
  13. TGF-β / Smad Signaling 8item
  14. Angiogenesis 2item
  15. GPCR/G protein 17item
  16. Stem Cell 17item
  17. Membrane Transporter/Ion Channel 12item
  18. Endocrinology and Hormones 6item
  19. Neuroscience 12item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Others 20item
  22. Immunology/Inflammation 6item
Reversibility
  1. Reversible 21item
  2. Irreversible 6item
Target
  1. Caspases 4item
  2. Cyclin-Dependent Kinases 14item
  3. Proteasome 4item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 12item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 3item
  8. Bcl-2 2item
  9. PI3K 13item
  10. CXCR 1 item
  11. Raf 3item
  12. Aurora Kinases 5item
  13. Glycoproteins 1 item
  14. MDM2 2item
  15. EZH2 2item
  16. mTOR 3item
  17. AP-1 2item
  18. MMP 4item
  19. Peptidylprolyl isomerases 1 item
  20. Myosin II ATPases 1 item
  21. DT-diaphorases 1 item
  22. MER 1 item
  23. FLT3 7item
  24. GSK-3 9item
  25. Factor Xa 1 item
  26. LPA Receptors 1 item
  27. P-glycoprotein (P-gp) 5item
  28. PLK 4item
  29. Chk 4item
  30. VEGFR 12item
  31. PDGFR 10item
  32. c-Kit 5item
  33. RET 2item
  34. Bromodomain-containing proteins(BRDs) 1 item
  35. Phosphodiesterases (PDEs) 2item
  36. Mcl-1 1 item
  37. Hydrolase 1 item
  38. p38 4item
  39. PKB 1 item
  40. JNK 1 item
  41. SGK 1 item
  42. Bcr-Abl 1 item
  43. Kynurenine-3-monooxygenase 1 item
  44. MEK 5item
  45. PORCN 1 item
  46. DOT1L 1 item
  47. FGFR 4item
  48. Nrf2 1 item
  49. Liver X receptors (LXRs) 1 item
  50. Glucagon-like peptide 1 (GLP-1) receptors 2item
  51. Voltage-gated Sodium (NaV) Channels 1 item
  52. Deubiquitinating enzymes (DUBs) 2item
  53. PP1 1 item
  54. PP2A 1 item
  55. Smoothened 3item
  56. MET 2item
  57. Src 1 item
  58. Trk Receptors 2item
  59. Aminopeptidases 1 item
  60. STAT 2item
  61. Microtubules/Tubulins 4item
  62. Estrogen and Related Receptors 1 item
  63. EGFR 5item
  64. Hedgehog 1 item
  65. ROCK 4item
  66. RIP kinases 1 item
  67. PAK 1 item
  68. JAK 3item
  69. p300 1 item
  70. Syk 1 item
  71. Progesterone Receptors 1 item
  72. DNA-PK 1 item
  73. HSP90 3item
  74. AMPK 3item
  75. CFTR 3item
  76. TNKS 1 item
  77. Topoisomerases 2item
  78. ErbB 2item
  79. Toll-like receptors (TLRs) 2item
  80. DNA Methyltransferases 1 item
  81. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  82. ERK 2item
  83. HMG-CoA Reductases 1 item
  84. c-MET 2item
  85. BMI-1 1 item
  86. PKC 1 item
  87. Ca2 /calmodulin-dependent protein kinases (CaMKs) 3item
  88. Lyn 1 item
  89. SGLT 1 item
  90. HER2 1 item
  91. 5-HT2 Receptors 1 item
  92. LRRK2 2item
  93. DGAT 1 item
  94. PARP 1 item
  95. ALK 1 item
  96. Sphingosine kinases (SphKs) 1 item
  97. CETP 1 item
  98. BCPCF efflux 1 item
  99. D2 Receptors 1 item
  100. 5-HT1 Receptors 1 item
  101. 5-HT7 Receptors 1 item
  102. AdipoR1 1 item
  103. AdipoR2 1 item
  104. Serotonin reuptake 1 item
  105. Insulin-like growth factors (IGFs) 1 item
  106. CSF1R 1 item
  107. MK2 2item
  108. Fatty-acid-binding proteins (FABPs) 1 item
  109. 5-HT3 Receptors 1 item
  110. Tie-2 1 item
  111. Free Fatty Acid Receptors 1 item
  112. phosphatases 1 item
  113. Autophagy 2item
  114. ATM/ATR 2item
  115. Histamine H4 Receptors 2item
  116. Farnesyl Diphosphate Synthases 1 item
  117. Melatonin Receptors 1 item
  118. P2X Receptors 1 item
  119. Ron 1 item
  120. Calcium-activated chloride channels (CaCC) 1 item
  121. GPR35 1 item
  122. MAGL 1 item
  123. NPY Receptors 1 item
  124. Histamine H1 Receptors 2item
  125. Na /K ATPases 1 item
  126. Histamine H2 Receptors 1 item
  127. Phospholipases 1 item
  128. TRP Channel 1 item
  129. NO Donors / Precursors 1 item
  130. Glucocorticoid Receptors 1 item
  131. IL Receptors 2item
  132. CCL2 1 item
  133. 15-lipoxygenases 1 item
  134. AChE 1 item
  135. Insulin Receptors 1 item
  136. IRG-1R 1 item
  137. Inward Rectifier Potassium (Kir) Channels 1 item
  138. Cdc7 1 item
  139. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  140. Aldosterone receptor 1 item
  141. Adenine receptors 1 item
  142. NAE 1 item
  143. Ubiquitin-activating Enzyme E1 1 item
  144. SUMOylation 1 item
  145. ATGL 1 item
  146. DPP-4 1 item
  147. DREADD Ligands 1 item
  148. PP4 1 item
  149. c-RET 1 item
  150. p53-MDM2 interaction 1 item
  151. HDAC 1 item
  152. c-Fms tyrosine kinase 1 item
  153. human lyase 1 item
  154. Ub-conjugating enzyme (E2) complex 1 item
  155. IKK 1 item
  156. Rev-Erb Receptors 1 item
  157. DCLK2 1 item
  158. NOP Receptors 1 item
  159. Bcl-w 1 item
  160. FXR 1 item
  161. Androgen Receptor 1 item
  162. Substance P/NK1 Receptor 1 item
  163. gp120/CD4 1 item
  164. Sirtuin 1 item
  165. CRF1 Receptors 1 item
  166. PIKfyve 1 item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 12item
  3. Advanced Renal Cell Carcinoma 1 item
  4. Autoimmune Diseases 1 item
  5. Bladder Cancer 5item
  6. B-lymphoid Malignancies 1 item
  7. Breast Cancer 54item
  8. Cancer 161item
  9. Cervical Cancer 2item
  10. Cholangiocarcinoma 1 item
  11. Chronic Lymphocytic Leukemia 2item
  12. Colon Cancer 17item
  13. Colon Carcinoma 2item
  14. Colorectal Cancer 24item
  15. Diabetes 4item
  16. Dyskinesia 1 item
  17. Dyslipidemia 2item
  18. Erectile Dysfunction 1 item
  19. Friedreich's Ataxia 1 item
  20. Fungal Infection 1 item
  21. Glioblastoma 12item
  22. Glioma 6item
  23. Heart Failure 1 item
  24. Hepatocellular Carcinoma 3item
  25. HIV 2item
  26. HIV Infections 1 item
  27. Immunosuppressive Therapy 1 item
  28. Inflammatory Diseases 6item
  29. Leukemia 7item
  30. Liver Cancer 3item
  31. Lung Cancer 13item
  32. Lymphoma 4item
  33. Mantle Cell Lymphoma 2item
  34. Medulloblastoma 1 item
  35. Melanoma 17item
  36. Mixed Lineage Leukemia 1 item
  37. Multiple Myeloma 9item
  38. Myelofibrosis 1 item
  39. Myeloma 1 item
  40. Narcolepsy 1 item
  41. Neuroblastoma 4item
  42. Non-small Cell Lung Cancer 10item
  43. Non-small Cell Lung Carcinoma 2item
  44. Ovarian Cancer 16item
  45. Pain Relief 1 item
  46. Pancreatic Cancer 18item
  47. Pancreatic Carcinoma 2item
  48. Prostate Cancer 22item
  49. Psoriasis 2item
  50. Pulmonary Arterial Hypertension 1 item
  51. Pulmonary Fibrosis 1 item
  52. Renal Cell Carcinoma 5item
  53. Rheumatoid Arthritis 3item
  54. Schizophrenia 2item
  55. Sleep Disorders 1 item
  56. Thyroid Cancer 2item
  57. Type 2 Diabetes 4item