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Search results for: 'research area stem cell stem gsk 3'

Search results for: 'research area stem cell stem gsk 3'

A3018 Trametinib (GSK1120212)

7 Citation

Target: MEK

Summary: MEK1 and MEK2 inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
A5057 MGCD-265

Target: VEGFR|c-MET

Summary: Met/Flt/Flk/Ron/Tie-2 inhibitor

≥25.9 mg/mL
B1036 MLN4924

5 Citation

Target: NAE|Ubiquitin-activating Enzyme E1|SUMOylation

Summary: NAE inhibitor

≥22.18 mg/mL
B3576 Omaveloxolone (RTA-408)

Target: Nrf2

Summary: Nrf2 activator

≥55.5 mg/mL
A4056 AT13387

Target: HSP90

Summary: Hsp90 inhibitor

insoluble in H2O; ≥13.25 mg/mL
A4097 CUDC-907

Target: Histone Deacetylases (HDACs)|PI3K

Summary: Potent PI3K/HDAC inhibitor

≥25.45 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A4102 CI994 (Tacedinaline)

1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥50 mg/mL
B2298 Plinabulin (NPI-2358)

Target: Vascular Disrupting Agents (VDA)

Summary: vascular disrupting agent

Soluble in DMSO
A3859 Tariquidar methanesulfonate, hydrate

Target: P-glycoprotein (P-gp)

Summary: P-glycoprotein inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥56.2 mg/mL