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Search results for: 'research area stem cell stem gsk 3'

Search results for: 'research area stem cell stem gsk 3'

A8340 Cyclopamine

1 Citation

Target: Smoothened

Summary: Hedgehog (Hh) signaling Inhibitor

insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
A3570 LY2090314

Target: GSK-3

Summary: Potent GSK-3 inhibitor

insoluble in H2O; ≥91 mg/mL
A3018 Trametinib (GSK1120212)

7 Citation

Target: MEK

Summary: MEK1 and MEK2 inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
A5459 PHA-793887

1 Citation

Target: Cyclin-Dependent Kinases

Summary: Pan-Cdk inhibitor

insoluble in H2O; ≥18.05 mg/mL
A8316 PD 0332991 (Palbociclib) HCl

5 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor,highly selective

≥14.48 mg/mL
N2791 Cucurbitacin E

Target: Actin

Summary: inhibits actin depolymerization

insoluble in EtOH; insoluble in H2O; ≥10.2 mg/mL
A2942 Masitinib (AB1010)

Target: PDGFR|c-Kit|Lyn

Summary: Tyrosine kinase inhibitor, potent and selective

≥24.95 mg/mL
B2266 LDE225 (NVP-LDE225,Erismodegib)

1 Citation

Target: Smoothened

Summary: Smoothened inhibitor,potent and selective

≥24.3 mg/mL
B2114 Mitoxantrone HCl

Target: Pim|Topoisomerases|USP|HIV Integrases

Summary: Topoisomerase II inhibitor, anti-neoplastic drug

insoluble in EtOH; ≥51.53 mg/mL
A4057 AUY922 (NVP-AUY922)

1 Citation

Target: HSP90

Summary: Potent Hsp90 inhibitor

≥23.27 mg/mL