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  • Search results for: 'research area stem cell wnt signaling'

Search results for: 'research area stem cell wnt signaling'

Items 11-20 of 183

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  1. Cucurbitacin I
    A4512 Cucurbitacin I
    Target: STAT|JAK
    Summary: STAT3/JAK2 signaling inhibitor
      ≥22.45 mg/mL
  2. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL
  3. EPZ005687
    A4171 EPZ005687
     2 Citation
    Target: EZH2
    Summary: EZH2 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
  4. WP1066
    A4140 WP1066
    Target: STAT|JAK
    Summary: JAK2/STAT3 inhibitor,cell-permeable
      insoluble in H2O; ≥17.8 mg/mL
  5. CCT251545
    B5979 CCT251545
    Summary: Orally bioavailable and potent WNT signaling inhibitor
      ≥42.2 mg/mL
  6. Stattic
    A2224 Stattic
     5 Citation
    Target: STAT
    Summary: STAT3 inhibitor,small-molecule and potent
      insoluble in H2O; insoluble in EtOH; ≥10.56 mg/mL
  7. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
  8. SB202190 (FHPI)
    A1632 SB202190 (FHPI)
     5 Citation
    Target: p38
    Summary: P38 MAPK inhibitor
  9. LY2090314
    A3570 LY2090314
    Target: GSK-3
    Summary: Potent GSK-3 inhibitor
      insoluble in H2O; ≥91 mg/mL
  10. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL

Items 11-20 of 183

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  1. Category Signaling Pathways Remove This Item
  2. Related Disease Cancer Remove This Item
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Category
  1. Proteases 8item
  2. Apoptosis 16item
  3. Chromatin/Epigenetics 23item
  4. Metabolism 4item
  5. MAPK Signaling 16item
  6. Tyrosine Kinase 18item
  7. DNA Damage/DNA Repair 23item
  8. PI3K/Akt/mTOR Signaling 25item
  9. Cell Cycle/Checkpoint 36item
  10. Ubiquitination/ Proteasome 10item
  11. JAK/STAT Signaling 15item
  12. TGF-β / Smad Signaling 13item
  13. GPCR/G protein 3item
  14. Stem Cell 18item
  15. Membrane Transporter/Ion Channel 2item
  16. Endocrinology and Hormones 1 item
  17. Others 4item
  18. Immunology/Inflammation 1 item
Specificity
  1. Selective 140item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 13item
  2. Irreversible 5item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 15item
  3. Proteasome 3item
  4. Histone Deacetylases (HDACs) 8item
  5. Inhibitor of apoptosis proteins (IAP) 1 item
  6. Akt 8item
  7. Bcl-2 2item
  8. PI3K 10item
  9. Raf 8item
  10. Aurora Kinases 4item
  11. Glycoproteins 1 item
  12. MDM2 1 item
  13. EZH2 3item
  14. mTOR 4item
  15. AP-1 1 item
  16. Androgen Receptors 1 item
  17. FLT3 1 item
  18. GSK-3 4item
  19. LPA Receptors 1 item
  20. P-glycoprotein (P-gp) 3item
  21. PLK 6item
  22. Chk 3item
  23. VEGFR 7item
  24. PDGFR 3item
  25. c-Kit 1 item
  26. Bromodomain-containing proteins(BRDs) 1 item
  27. Phosphodiesterases (PDEs) 1 item
  28. p38 2item
  29. JNK 1 item
  30. MEK 5item
  31. PORCN 1 item
  32. DOT1L 1 item
  33. FGFR 2item
  34. Deubiquitinating enzymes (DUBs) 1 item
  35. Smoothened 2item
  36. Trk Receptors 1 item
  37. STAT 5item
  38. Microtubules/Tubulins 4item
  39. EGFR 6item
  40. Hedgehog 1 item
  41. ROCK 1 item
  42. BMP and Other Activin Receptors 1 item
  43. JAK 4item
  44. p300 1 item
  45. DNA-PK 2item
  46. HSP90 1 item
  47. TNKS 1 item
  48. ErbB 2item
  49. DNA Methyltransferases 1 item
  50. ERK 2item
  51. BMI-1 1 item
  52. PKC 7item
  53. Lyn 1 item
  54. SGLT 1 item
  55. RAD51 1 item
  56. ALK 1 item
  57. Sphingosine kinases (SphKs) 1 item
  58. PKG 1 item
  59. PKA 4item
  60. RSK 1 item
  61. Autophagy 2item
  62. ATM/ATR 3item
  63. CK1 1 item
  64. Farnesyl Diphosphate Synthases 1 item
  65. MAGL 1 item
  66. Apoptosis Inducers 1 item
  67. MNK 1 item
  68. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  69. BACE 1 item
  70. p70 rsk 2item
  71. Microtubule/Tubulin 1 item
  72. p53-MDM2 interaction 1 item
  73. KDR 1 item
  74. p53 2item
  75. insulin 1 item
  76. Ub-conjugating enzyme (E2) complex 1 item
  77. Smoothened receptor 1 item
  78. HDM2 ubiquitin ligase 1 item
  79. Antibiotic 1 item
  80. DNA Alkylating 1 item
  81. GLI 1 item
  82. Prk 1 item
  83. Ribonucleotide Reductases 1 item
  84. Flk1 1 item
  85. RHA 1 item
  86. Bcl-w 1 item
  87. PPK 1 item
  88. c-Syk 1 item
  89. CDK1/CyclinB 1 item
  90. Bax 1 item
Reported Experiments
  1. Animal Experiments 172item
  2. Cell Experiments 112item