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  • Search results for: 'research area tyrosine kinase fak'

Search results for: 'research area tyrosine kinase fak'

Items 111-120 of 199

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  1. BLZ945
    B4899 BLZ945
     1 Citation
    Target: CSF-1R
    Summary: CSF-1R kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.9 mg/mL
  2. PLX-4720
    A3016 PLX-4720
     1 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥20.69 mg/mL
  3. Defactinib
    B4800 Defactinib
    Target: FAK
    Summary: FAK phosphorylation inhibitor
      insoluble in EtOH; insoluble in H2O; ≥160.2 mg/mL
  4. MGCD-265
    A5057 MGCD-265
    Target: VEGFR|c-MET
    Summary: Met/Flt/Flk/Ron/Tie-2 inhibitor
      ≥25.9 mg/mL
  5. OTSSP167
    B1321 OTSSP167
    Target: MELK
    Summary: MELK inhibitor
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  6. LY2109761
    A8464 LY2109761
     4 Citation
    Summary: TβRI/II kinase inhibitor
      ≥22.1 mg/mL
  7. GW2580
    A1655 GW2580
     1 Citation
    Target: CSF-1R
    Summary: CFMS kinase/CSF-1R inhibitor,selective and ATP-competitive
      ≥36.6 mg/mL
  8. Gemcitabine
    A8437 Gemcitabine
     1 Citation
    Summary: inhibitor of DNA synthesis
      ≥11.75 mg/mL
  9. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  10. Axitinib (AG 013736)
    A8370 Axitinib (AG 013736)
     1 Citation
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR1/ c-Kit inhibitor
      insoluble in H2O; ≥19.3 mg/mL

Items 111-120 of 199

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  1. Category Signaling Pathways Remove This Item
  2. Related Disease Cancer Remove This Item
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Category
  1. Apoptosis 5item
  2. Chromatin/Epigenetics 25item
  3. MAPK Signaling 14item
  4. Tyrosine Kinase 81item
  5. DNA Damage/DNA Repair 7item
  6. PI3K/Akt/mTOR Signaling 24item
  7. Cell Cycle/Checkpoint 52item
  8. Ubiquitination/ Proteasome 3item
  9. JAK/STAT Signaling 22item
  10. TGF-β / Smad Signaling 16item
  11. GPCR/G protein 1 item
  12. Stem Cell 3item
  13. Others 5item
  14. Immunology/Inflammation 1 item
Specificity
  1. Selective 155item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 18item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 4item
  4. PI3K 11item
  5. Raf 9item
  6. Aurora Kinases 16item
  7. CSF-1R 4item
  8. mTOR 5item
  9. FLT3 7item
  10. GSK-3 4item
  11. PLK 5item
  12. Chk 4item
  13. Eph Receptors 3item
  14. VEGFR 27item
  15. PDGFR 17item
  16. c-Kit 9item
  17. RET 4item
  18. Bromodomain-containing proteins(BRDs) 1 item
  19. p38 3item
  20. JNK 1 item
  21. SGK 2item
  22. Bcr-Abl 6item
  23. MEK 2item
  24. FGFR 9item
  25. Pim 3item
  26. Ribosomal s6 kinases (RSK) 1 item
  27. MET 5item
  28. Src 8item
  29. Trk Receptors 1 item
  30. STAT 2item
  31. EGFR 13item
  32. PAK 3item
  33. FAK 6item
  34. BMP and Other Activin Receptors 1 item
  35. JAK 8item
  36. Syk 3item
  37. DNA-PK 4item
  38. ErbB 4item
  39. ERK 2item
  40. c-MET 5item
  41. PKC 8item
  42. Ubiquitin-specific proteases 1 item
  43. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  44. Lyn 1 item
  45. HER2 1 item
  46. Pyk2 3item
  47. Insulin and Insulin-like Receptors 2item
  48. ALK 5item
  49. ROS1 1 item
  50. Sphingosine kinases (SphKs) 1 item
  51. PKG 2item
  52. PKA 4item
  53. Myosin light chain kinases (MLCKs) 1 item
  54. MELK 1 item
  55. Insulin-like growth factors (IGFs) 1 item
  56. MK2 1 item
  57. Tie-2 1 item
  58. RSK 1 item
  59. ATM/ATR 3item
  60. CK1 1 item
  61. Farnesyl Diphosphate Synthases 1 item
  62. CK2 1 item
  63. HIPK2 1 item
  64. HIPK3 1 item
  65. P110 1 item
  66. Hck 1 item
  67. MNK 1 item
  68. Insulin Receptors 1 item
  69. IRG-1R 1 item
  70. eEF-2 1 item
  71. Cdc7 1 item
  72. ZAP-70 1 item
  73. c-RET 2item
  74. p70 rsk 1 item
  75. VEGFR3/FLT4 1 item
  76. NTRK1/TRKA 1 item
  77. CSF-1R/c-Fms 1 item
  78. TAM kinase 1 item
  79. KDR 1 item
  80. AXL 1 item
  81. insulin 1 item
  82. ErbB-2 1 item
  83. PDK-1 1 item
  84. Prk 1 item
  85. Flk1 2item
  86. tropomyosin receptor kinase 1 item
  87. SK 1 item
  88. PPK 1 item
  89. c-Syk 1 item
  90. CDK1/CyclinB 1 item
  91. PIM1 kinase 1 item
  92. phospholipase A2 1 item
Reported Experiments
  1. Animal Experiments 186item
  2. Cell Experiments 123item