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  • Search results for: 'research area tyrosine kinase fak'

Search results for: 'research area tyrosine kinase fak'

Items 51-60 of 657

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  1. Gefitinib (ZD1839)
    A8219 Gefitinib (ZD1839)
     3 Citation
    Target: EGFR
    Summary: Selective EGFR inhibitor
      ≥22.34 mg/mL
  2. AZD4547
    A8350 AZD4547
    Target: FGFR
    Summary: FGFR inhibitor
      ≥23.2 mg/mL
  3. LDK378
    A8328 LDK378
    Target: ALK
    Summary: Potent ALK inhibitor
      insoluble in H2O; ≥13.95 mg/mL
  4. LDK378 dihydrochloride
    A3544 LDK378 dihydrochloride
    Summary: ALK inhibitor
  5. Pazopanib (GW-786034)
    A3022 Pazopanib (GW-786034)
    Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL
  6. AEE788 (NVP-AEE788)
    A5455 AEE788 (NVP-AEE788)
    Summary: EGFR/HER-2/VEGFR inhibitor
      ≥22.05 mg/mL
  7. Dasatinib (BMS-354825)
    A3017 Dasatinib (BMS-354825)
     4 Citation
    Summary: Src and BCR-Abl inhibitor
      ≥24.4 mg/mL
  8. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  9. Danusertib (PHA-739358)
    A4116 Danusertib (PHA-739358)
     2 Citation
    Target: Aurora Kinases
    Summary: Pan-aurora kinase inhibitor
      ≥23.75 mg/mL
  10. XL228
    A3939 XL228
    Summary: IGF1R/AURORA /FGFR1-3/ABL/SRC family kinases inhibitor
      ≥21.9 mg/mL

Items 51-60 of 657

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Proteases 2item
  2. Apoptosis 21item
  3. Chromatin/Epigenetics 71item
  4. Metabolism 5item
  5. MAPK Signaling 61item
  6. Tyrosine Kinase 225item
  7. DNA Damage/DNA Repair 15item
  8. PI3K/Akt/mTOR Signaling 76item
  9. Microbiology & Virology 2item
  10. Cell Cycle/Checkpoint 116item
  11. Ubiquitination/ Proteasome 7item
  12. JAK/STAT Signaling 62item
  13. TGF-β / Smad Signaling 71item
  14. Angiogenesis 6item
  15. GPCR/G protein 5item
  16. Stem Cell 12item
  17. Membrane Transporter/Ion Channel 6item
  18. Cancer Biology 6item
  19. Neuroscience 6item
  20. Other Signal Transduction 5item
  21. Others 34item
  22. Immunology/Inflammation 11item
Specificity
  1. Selective 242item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 24item
  2. Irreversible 8item
Target
  1. Cyclin-Dependent Kinases 27item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 4item
  4. PI3K 16item
  5. Raf 10item
  6. Aurora Kinases 21item
  7. CSF-1R 4item
  8. mTOR 8item
  9. FLT3 13item
  10. GSK-3 9item
  11. PLK 6item
  12. Chk 5item
  13. Eph Receptors 3item
  14. VEGFR 30item
  15. PDGFR 22item
  16. c-Kit 12item
  17. RET 4item
  18. IRAK 3item
  19. Bromodomain-containing proteins(BRDs) 1 item
  20. p38 6item
  21. PKB 1 item
  22. JNK 2item
  23. SGK 2item
  24. Bcr-Abl 13item
  25. MEK 4item
  26. FGFR 12item
  27. Pim 4item
  28. Voltage-gated Sodium (NaV) Channels 1 item
  29. Ribosomal s6 kinases (RSK) 1 item
  30. MET 5item
  31. Src 17item
  32. Trk Receptors 2item
  33. STAT 3item
  34. EGFR 18item
  35. ROCK 7item
  36. BTK 1 item
  37. PAK 3item
  38. FAK 6item
  39. BMP and Other Activin Receptors 2item
  40. JAK 16item
  41. Syk 5item
  42. DNA-PK 5item
  43. AMPK 2item
  44. PDHK 1 item
  45. ErbB 4item
  46. S6 kinases 1 item
  47. Adenosine Kinases 2item
  48. ERK 4item
  49. Kinases 1 item
  50. c-MET 5item
  51. PKC 12item
  52. Ubiquitin-specific proteases 1 item
  53. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  54. Lyn 2item
  55. HER2 2item
  56. Pyk2 3item
  57. LRRK2 5item
  58. Insulin and Insulin-like Receptors 3item
  59. ALK 6item
  60. ROS1 1 item
  61. Sphingosine kinases (SphKs) 2item
  62. PKG 2item
  63. PKA 5item
  64. Myosin light chain kinases (MLCKs) 2item
  65. CaM-KK 1 item
  66. MELK 1 item
  67. Insulin-like growth factors (IGFs) 1 item
  68. Clk 1 item
  69. NUAK1 1 item
  70. NUAK2 1 item
  71. MK2 2item
  72. Fatty-acid-binding proteins (FABPs) 1 item
  73. Angiotensin-Converting Enzymes (ACEs) 1 item
  74. Tie-2 2item
  75. RSK 2item
  76. ATM/ATR 4item
  77. CK1 1 item
  78. Farnesyl Diphosphate Synthases 1 item
  79. CK2 3item
  80. HIPK2 1 item
  81. HIPK3 1 item
  82. P2X Receptors 1 item
  83. c-Fyn 1 item
  84. TAK1 1 item
  85. Histamine H1 Receptors 1 item
  86. P110 1 item
  87. Hck 2item
  88. MNK 1 item
  89. 5-Lipoxygenases 1 item
  90. Insulin Receptors 1 item
  91. IRG-1R 1 item
  92. eEF-2 1 item
  93. Cdc7 1 item
  94. ZAP-70 1 item
  95. c-RET 3item
  96. p70 rsk 2item
  97. VEGFR3/FLT4 1 item
  98. NTRK1/TRKA 1 item
  99. CSF-1R/c-Fms 1 item
  100. TAM kinase 1 item
  101. KDR 1 item
  102. Fyn kinase 1 item
  103. Abl kinases 1 item
  104. AXL 1 item
  105. c-Fms tyrosine kinase 1 item
  106. insulin 1 item
  107. haspin kinase 1 item
  108. STK 1 item
  109. MSK 1 item
  110. Lyn kinase 1 item
  111. Mer tyrosine kinase 1 item
  112. ErbB-2 1 item
  113. PDK-1 1 item
  114. Histone Acetyltransferases (HATs) 1 item
  115. Prk 1 item
  116. ITK 1 item
  117. NUAK 1 item
  118. DCLK2 1 item
  119. PTK 1 item
  120. phosphatidylinositol kinase 1 item
  121. Lck 1 item
  122. Flk1 2item
  123. Protein Tyrosine Phosphatases 1 item
  124. alkaline phosphatases 1 item
  125. ATPases 1 item
  126. glutamate release 1 item
  127. FGR 1 item
  128. YES 2item
  129. Fyn 2item
  130. ARG 1 item
  131. TRPC channel 1 item
  132. PKD 1 item
  133. enoyl-acyl-carrier protein reductase 1 item
  134. Rho-kinase 1 item
  135. tropomyosin receptor kinase 1 item
  136. SK 1 item
  137. PPK 1 item
  138. c-Syk 1 item
  139. CDK1/CyclinB 1 item
  140. PIM1 kinase 1 item
  141. phospholipase A2 1 item
  142. ATM 1 item
  143. PIKfyve 1 item
  144. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 282item
  2. Cell Experiments 207item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 16item
  3. Adrenocortical Carcinoma 2item
  4. Advanced Renal Cell Carcinoma 1 item
  5. Bladder Cancer 4item
  6. Bladder Carcinoma 1 item
  7. B-lymphoid Malignancies 1 item
  8. Breast Cancer 44item
  9. Cancer 199item
  10. Cervical Cancer 4item
  11. Cholangiocarcinoma 2item
  12. Chronic Lymphocytic Leukemia 2item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 20item
  15. Colon Carcinoma 2item
  16. Colorectal Cancer 19item
  17. Diabetes 1 item
  18. Glioblastoma 17item
  19. Glioma 7item
  20. Hepatocellular Carcinoma 4item
  21. HIV Infections 1 item
  22. Immunological Diseases 1 item
  23. Inflammatory Bowel Disease 1 item
  24. Inflammatory Diseases 4item
  25. Leukemia 8item
  26. Liver Cancer 3item
  27. Lung Cancer 15item
  28. Lung Carcinoma 3item
  29. Lymphoma 9item
  30. Mantle Cell Lymphoma 1 item
  31. Melanoma 12item
  32. Multiple Myeloma 6item
  33. Myelofibrosis 1 item
  34. Myeloma 1 item
  35. Neuroblastoma 2item
  36. Non-small Cell Lung Cancer 5item
  37. Non-small Cell Lung Carcinoma 1 item
  38. Ovarian Cancer 15item
  39. Pancreatic Cancer 22item
  40. Prostate Cancer 17item
  41. Psoriasis 1 item
  42. Pulmonary Arterial Hypertension 1 item
  43. Renal Cancer 3item
  44. Renal Cell Carcinoma 5item
  45. Rheumatoid Arthritis 5item
  46. Thyroid Cancer 5item
  47. Type 2 Diabetes 3item