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  • Search results for: 'research area tyrosine kinase igf1r'

Search results for: 'research area tyrosine kinase igf1r'

Items 41-50 of 281

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  1. SGX-523
    A1196 SGX-523
     1 Citation
    Target: MET
    Summary: MET inibitor, highly selective, ATP-competitive
      ≥17.95 mg/mL
  2. Brivanib (BMS-540215)
    A2597 Brivanib (BMS-540215)
    Target: VEGFR|FGFR|Flk1
    Summary: VEGFR-2 inhibitor,ATP-competitive
      insoluble in H2O; ≥18.5 mg/mL
  3. Lenvatinib (E7080)
    A2174 Lenvatinib (E7080)
    Target: VEGFR|PDGFR|RET
    Summary: VEGFR inhibitor
      ≥21.35 mg/mL
  4. Quizartinib (AC220)
    A5793 Quizartinib (AC220)
    Target: FLT3
    Summary: FLT3 inhibitor,potent and selective
      ≥28.03 mg/mL
  5. Crenolanib (CP-868596)
    A8307 Crenolanib (CP-868596)
     1 Citation
    Target: FLT3|PDGFR
    Summary: PDGFR-β inhibitor,potent and selective
      ≥22.2 mg/mL
  6. Tivantinib (ARQ 197)
    A8325 Tivantinib (ARQ 197)
     2 Citation
    Target: MET
    Summary: C-Met inhibitor,non-ATP-competitive
      ≥18.47 mg/mL
  7. R428
    A8329 R428
     10 Citation
    Summary: Selective Axl inhibitor
      ≥25 mg/mL
  8. GSK1838705A
    A8440 GSK1838705A
    Target: Insulin and Insulin-like Receptors|ALK
    Summary: IGF-IR/IR/ALK inhibitor, ATP-competitive
      ≥26.65 mg/mL
  9. TAK-285
    A8528 TAK-285
    Target: EGFR|HER2
    Summary: HER2/EGFR(HER1) inhibitor
      ≥27.4 mg/mL
  10. CH5424802
    A8393 CH5424802
    Target: ALK
    Summary: ALK inhibitor,potent and ATP-competitive

Items 41-50 of 281

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Category
  1. Apoptosis 6item
  2. Chromatin/Epigenetics 32item
  3. Metabolism 1 item
  4. MAPK Signaling 22item
  5. Tyrosine Kinase 106item
  6. DNA Damage/DNA Repair 6item
  7. PI3K/Akt/mTOR Signaling 38item
  8. Microbiology & Virology 1 item
  9. Cell Cycle/Checkpoint 57item
  10. Ubiquitination/ Proteasome 3item
  11. JAK/STAT Signaling 29item
  12. TGF-β / Smad Signaling 33item
  13. Angiogenesis 1 item
  14. GPCR/G protein 3item
  15. Stem Cell 5item
  16. Membrane Transporter/Ion Channel 5item
  17. Neuroscience 2item
  18. Others 11item
  19. Immunology/Inflammation 1 item
Specificity
  1. Selective 210item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 22item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 4item
  4. PI3K 14item
  5. Raf 10item
  6. Aurora Kinases 18item
  7. CSF-1R 4item
  8. mTOR 7item
  9. FLT3 13item
  10. GSK-3 8item
  11. PLK 6item
  12. Chk 5item
  13. Eph Receptors 2item
  14. VEGFR 30item
  15. PDGFR 22item
  16. c-Kit 12item
  17. RET 4item
  18. IRAK 1 item
  19. Bromodomain-containing proteins(BRDs) 1 item
  20. p38 6item
  21. PKB 1 item
  22. JNK 1 item
  23. SGK 1 item
  24. Bcr-Abl 11item
  25. MEK 3item
  26. FGFR 12item
  27. Insulin-like growth factor receptors(IGFRs) 1 item
  28. Pim 3item
  29. Voltage-gated Sodium (NaV) Channels 1 item
  30. MET 5item
  31. Src 14item
  32. Trk Receptors 2item
  33. STAT 3item
  34. EGFR 16item
  35. ROCK 5item
  36. BTK 1 item
  37. PAK 3item
  38. FAK 4item
  39. BMP and Other Activin Receptors 2item
  40. JAK 14item
  41. Syk 5item
  42. DNA-PK 4item
  43. AMPK 2item
  44. PDHK 1 item
  45. ErbB 4item
  46. S6 kinases 1 item
  47. Adenosine Kinases 2item
  48. ERK 4item
  49. c-MET 5item
  50. PKC 11item
  51. Ubiquitin-specific proteases 1 item
  52. Ca2 /calmodulin-dependent protein kinases (CaMKs) 5item
  53. Lyn 2item
  54. HER2 2item
  55. Pyk2 3item
  56. LRRK2 5item
  57. Insulin and Insulin-like Receptors 3item
  58. ALK 6item
  59. ROS1 1 item
  60. Sphingosine kinases (SphKs) 2item
  61. PKG 1 item
  62. PKA 4item
  63. Myosin light chain kinases (MLCKs) 1 item
  64. MELK 1 item
  65. Insulin-like growth factors (IGFs) 1 item
  66. MK2 2item
  67. Fatty-acid-binding proteins (FABPs) 1 item
  68. Angiotensin-Converting Enzymes (ACEs) 1 item
  69. Tie-2 2item
  70. RSK 2item
  71. ATM/ATR 2item
  72. Farnesyl Diphosphate Synthases 1 item
  73. CK2 2item
  74. HIPK2 1 item
  75. HIPK3 1 item
  76. P2X Receptors 1 item
  77. Histamine H1 Receptors 1 item
  78. P110 1 item
  79. Hck 2item
  80. MNK 1 item
  81. 5-Lipoxygenases 1 item
  82. Insulin Receptors 1 item
  83. IRG-1R 1 item
  84. eEF-2 1 item
  85. Cdc7 1 item
  86. ZAP-70 1 item
  87. c-RET 3item
  88. p70 rsk 2item
  89. VEGFR3/FLT4 1 item
  90. NTRK1/TRKA 1 item
  91. CSF-1R/c-Fms 1 item
  92. TAM kinase 1 item
  93. KDR 1 item
  94. Fyn kinase 1 item
  95. AXL 1 item
  96. c-Fms tyrosine kinase 1 item
  97. insulin 1 item
  98. MSK 1 item
  99. Lyn kinase 1 item
  100. Mer tyrosine kinase 1 item
  101. ErbB-2 1 item
  102. PDK-1 1 item
  103. Histone Acetyltransferases (HATs) 1 item
  104. Prk 1 item
  105. ITK 1 item
  106. NUAK 1 item
  107. DCLK2 1 item
  108. PTK 1 item
  109. phosphatidylinositol kinase 1 item
  110. Flk1 2item
  111. Protein Tyrosine Phosphatases 1 item
  112. alkaline phosphatases 1 item
  113. ATPases 1 item
  114. glutamate release 1 item
  115. FGR 1 item
  116. YES 2item
  117. Fyn 2item
  118. ARG 1 item
  119. TRPC channel 1 item
  120. PKD 1 item
  121. enoyl-acyl-carrier protein reductase 1 item
  122. Rho-kinase 1 item
  123. tropomyosin receptor kinase 1 item
  124. SK 1 item
  125. PPK 1 item
  126. c-Syk 1 item
  127. CDK1/CyclinB 1 item
  128. PIM1 kinase 1 item
  129. phospholipase A2 1 item
  130. PIKfyve 1 item
  131. Insulin Receptor 1 item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 15item
  3. Adrenocortical Carcinoma 2item
  4. Advanced Renal Cell Carcinoma 1 item
  5. Bladder Cancer 4item
  6. Bladder Carcinoma 1 item
  7. B-lymphoid Malignancies 1 item
  8. Breast Cancer 42item
  9. Cancer 185item
  10. Cervical Cancer 4item
  11. Cholangiocarcinoma 2item
  12. Chronic Lymphocytic Leukemia 2item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 18item
  15. Colon Carcinoma 3item
  16. Colorectal Cancer 18item
  17. Glioblastoma 17item
  18. Glioma 6item
  19. Hepatocellular Carcinoma 4item
  20. HIV Infections 1 item
  21. Immunological Diseases 1 item
  22. Inflammatory Bowel Disease 1 item
  23. Inflammatory Diseases 3item
  24. Leukemia 8item
  25. Liver Cancer 3item
  26. Lung Cancer 14item
  27. Lung Carcinoma 3item
  28. Lymphoma 9item
  29. Mantle Cell Lymphoma 1 item
  30. Melanoma 11item
  31. Multiple Myeloma 4item
  32. Myelofibrosis 1 item
  33. Myeloma 2item
  34. Neuroblastoma 2item
  35. Non-small Cell Lung Cancer 6item
  36. Non-small Cell Lung Carcinoma 1 item
  37. Ovarian Cancer 14item
  38. Pancreatic Cancer 22item
  39. Prostate Cancer 14item
  40. Psoriasis 1 item
  41. Pulmonary Arterial Hypertension 1 item
  42. Renal Cancer 3item
  43. Renal Cell Carcinoma 5item
  44. Rheumatoid Arthritis 5item
  45. Thyroid Cancer 5item
  46. Type 2 Diabetes 3item