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  • Search results for: 'research area tyrosine kinase igf1r'

Search results for: 'research area tyrosine kinase igf1r'

Items 151-160 of 284

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  1. Gemcitabine
    A8437 Gemcitabine
     1 Citation
    Summary: inhibitor of DNA synthesis
      ≥11.75 mg/mL
  2. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  3. Axitinib (AG 013736)
    A8370 Axitinib (AG 013736)
     1 Citation
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR1/ c-Kit inhibitor
      insoluble in H2O; ≥19.3 mg/mL
  4. Dovitinib (TKI258) Lactate
    B5953 Dovitinib (TKI258) Lactate
    Target: CSF-1R|FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).
      insoluble in EtOH; ≥10.62 mg/mL
  5. AZD7762
    A5919 AZD7762
    Target: Chk
    Summary: Checkpoint kinase inhibitor,ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥18.1 mg/mL
  6. AMG 925
    B3277 AMG 925
    Target: Cyclin-Dependent Kinases|FLT3
    Summary: FLT3/CDK4 inhibitor,potent and selective
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  7. Sotrastaurin (AEB071)
    A8525 Sotrastaurin (AEB071)
    Target: PKC
    Summary: PKC inhibitor
      ≥21.9 mg/mL
  8. GF 109203X
    A8342 GF 109203X
     1 Citation
    Target: PKC
    Summary: Protein kinase C,MLCK,PKG and PKA inhibitor
      insoluble in EtOH; insoluble in H2O; ≥20.6 mg/mL
  9. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  10. PD153035 hydrochloride
    A8199 PD153035 hydrochloride
     1 Citation
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥3.97 mg/mL

Items 151-160 of 284

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  1. Reported Experiments Animal Experiments Remove This Item
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Category
  1. Signaling Pathways 281item
  2. Natural Products 1 item
  3. Lab Reagents 1 item
Specificity
  1. Selective 211item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 22item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 4item
  4. PI3K 14item
  5. Raf 10item
  6. Aurora Kinases 18item
  7. CSF-1R 4item
  8. mTOR 7item
  9. FLT3 13item
  10. GSK-3 8item
  11. PLK 6item
  12. Chk 5item
  13. Eph Receptors 2item
  14. VEGFR 30item
  15. PDGFR 22item
  16. c-Kit 12item
  17. RET 4item
  18. IRAK 1 item
  19. Bromodomain-containing proteins(BRDs) 1 item
  20. p38 6item
  21. PKB 1 item
  22. JNK 1 item
  23. SGK 1 item
  24. Bcr-Abl 11item
  25. MEK 3item
  26. FGFR 12item
  27. Insulin-like growth factor receptors(IGFRs) 1 item
  28. Pim 3item
  29. Voltage-gated Sodium (NaV) Channels 1 item
  30. MET 5item
  31. Src 14item
  32. Trk Receptors 2item
  33. STAT 3item
  34. EGFR 16item
  35. ROCK 5item
  36. BTK 1 item
  37. PAK 3item
  38. FAK 4item
  39. BMP and Other Activin Receptors 2item
  40. JAK 14item
  41. Syk 5item
  42. DNA-PK 4item
  43. AMPK 2item
  44. PDHK 1 item
  45. Cytochrome P450 (CYP450) 1 item
  46. ErbB 4item
  47. S6 kinases 1 item
  48. Adenosine Kinases 2item
  49. ERK 4item
  50. c-MET 5item
  51. PKC 11item
  52. Ubiquitin-specific proteases 1 item
  53. Ca2 /calmodulin-dependent protein kinases (CaMKs) 5item
  54. Lyn 2item
  55. HER2 2item
  56. Pyk2 3item
  57. LRRK2 5item
  58. Insulin and Insulin-like Receptors 3item
  59. ALK 6item
  60. ROS1 1 item
  61. Sphingosine kinases (SphKs) 2item
  62. PKG 1 item
  63. PKA 4item
  64. Myosin light chain kinases (MLCKs) 1 item
  65. MELK 1 item
  66. Insulin-like growth factors (IGFs) 1 item
  67. MK2 2item
  68. Fatty-acid-binding proteins (FABPs) 1 item
  69. Angiotensin-Converting Enzymes (ACEs) 1 item
  70. Tie-2 2item
  71. RSK 2item
  72. phosphatases 1 item
  73. ATM/ATR 2item
  74. Farnesyl Diphosphate Synthases 1 item
  75. CK2 2item
  76. HIPK2 1 item
  77. HIPK3 1 item
  78. P2X Receptors 1 item
  79. Histamine H1 Receptors 1 item
  80. P110 1 item
  81. Hck 2item
  82. MNK 1 item
  83. 5-Lipoxygenases 1 item
  84. Insulin Receptors 1 item
  85. IRG-1R 1 item
  86. Cdc2-like kinase (Clk) 1 item
  87. eEF-2 1 item
  88. Cdc7 1 item
  89. ZAP-70 1 item
  90. c-RET 3item
  91. p70 rsk 2item
  92. VEGFR3/FLT4 1 item
  93. NTRK1/TRKA 1 item
  94. CSF-1R/c-Fms 1 item
  95. TAM kinase 1 item
  96. KDR 1 item
  97. Fyn kinase 1 item
  98. AXL 1 item
  99. c-Fms tyrosine kinase 1 item
  100. insulin 1 item
  101. MSK 1 item
  102. Lyn kinase 1 item
  103. Mer tyrosine kinase 1 item
  104. ErbB-2 1 item
  105. PDK-1 1 item
  106. Histone Acetyltransferases (HATs) 1 item
  107. Prk 1 item
  108. ITK 1 item
  109. NUAK 1 item
  110. DCLK2 1 item
  111. PTK 1 item
  112. phosphatidylinositol kinase 1 item
  113. Flk1 2item
  114. Protein Tyrosine Phosphatases 1 item
  115. alkaline phosphatases 1 item
  116. ATPases 1 item
  117. glutamate release 1 item
  118. FGR 1 item
  119. YES 2item
  120. Fyn 2item
  121. ARG 1 item
  122. TRPC channel 1 item
  123. PKD 1 item
  124. Pyruvate kinases 1 item
  125. enoyl-acyl-carrier protein reductase 1 item
  126. Rho-kinase 1 item
  127. tropomyosin receptor kinase 1 item
  128. SK 1 item
  129. PPK 1 item
  130. c-Syk 1 item
  131. CDK1/CyclinB 1 item
  132. PIM1 kinase 1 item
  133. phospholipase A2 1 item
  134. PIKfyve 1 item
  135. Insulin Receptor 1 item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 15item
  3. Adrenocortical Carcinoma 2item
  4. Advanced Renal Cell Carcinoma 1 item
  5. Bladder Cancer 4item
  6. Bladder Carcinoma 1 item
  7. B-lymphoid Malignancies 1 item
  8. Breast Cancer 42item
  9. Cancer 185item
  10. Cervical Cancer 4item
  11. Cholangiocarcinoma 2item
  12. Chronic Lymphocytic Leukemia 2item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 18item
  15. Colon Carcinoma 3item
  16. Colorectal Cancer 18item
  17. Glioblastoma 17item
  18. Glioma 6item
  19. Hepatocellular Carcinoma 4item
  20. HIV Infections 1 item
  21. Immunological Diseases 1 item
  22. Inflammatory Bowel Disease 1 item
  23. Inflammatory Diseases 3item
  24. Leukemia 8item
  25. Liver Cancer 3item
  26. Lung Cancer 14item
  27. Lung Carcinoma 3item
  28. Lymphoma 9item
  29. Mantle Cell Lymphoma 1 item
  30. Melanoma 11item
  31. Multiple Myeloma 4item
  32. Myelofibrosis 1 item
  33. Myeloma 2item
  34. Neuroblastoma 2item
  35. Non-small Cell Lung Cancer 6item
  36. Non-small Cell Lung Carcinoma 1 item
  37. Ovarian Cancer 14item
  38. Pancreatic Cancer 22item
  39. Prostate Cancer 14item
  40. Psoriasis 1 item
  41. Pulmonary Arterial Hypertension 1 item
  42. Renal Cancer 3item
  43. Renal Cell Carcinoma 5item
  44. Rheumatoid Arthritis 5item
  45. Thyroid Cancer 5item
  46. Type 2 Diabetes 3item