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  • Search results for: 'research area tyrosine kinase src'

Search results for: 'research area tyrosine kinase src'

Items 131-140 of 242

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  1. AMG 925
    B3277 AMG 925
    Target: Cyclin-Dependent Kinases|FLT3
    Summary: FLT3/CDK4 inhibitor,potent and selective
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  2. Sotrastaurin (AEB071)
    A8525 Sotrastaurin (AEB071)
    Target: PKC
    Summary: PKC inhibitor
      ≥21.9 mg/mL
  3. ML167
    B3707 ML167
    Target: Clk
    Summary: Clk4 inhibitor,highly selective
      insoluble in EtOH; insoluble in H2O; ≥16.75 mg/mL
  4. GF 109203X
    A8342 GF 109203X
     1 Citation
    Target: PKC
    Summary: Protein kinase C,MLCK,PKG and PKA inhibitor
      insoluble in EtOH; insoluble in H2O; ≥20.6 mg/mL
  5. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  6. AZD2932
    B5835 AZD2932
    Target: FLT3|VEGFR|PDGFR|c-Kit
    Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit
      Soluble in DMSO
  7. FMK
    A3420 FMK
    Target: Ribosomal s6 kinases (RSK)
    Summary: RSK inhibitor
      insoluble in H2O; ≥17.1 mg/mL
  8. Y-27632 dihydrochloride
    A3008 Y-27632 dihydrochloride
     19 Citation
    Target: ROCK
    Summary: ROCK1 inhibitor
      ≥111.2 mg/mL
  9. KN-93
    A3532 KN-93
    Target: Ca2 /calmodulin-dependent protein kinases (CaMKs)
    Summary: CaMKII inhibitor,selective and cometitive
      insoluble in H2O; ≥19.15 mg/mL
  10. TGX-221
    A2681 TGX-221
    Target: PI3K
    Summary: PI3Kβ inhibitor,potent,selective and ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL

Items 131-140 of 242

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Category
  1. Apoptosis 3item
  2. Chromatin/Epigenetics 24item
  3. Metabolism 1 item
  4. MAPK Signaling 20item
  5. Tyrosine Kinase 86item
  6. DNA Damage/DNA Repair 6item
  7. PI3K/Akt/mTOR Signaling 34item
  8. Cell Cycle/Checkpoint 54item
  9. Ubiquitination/ Proteasome 3item
  10. JAK/STAT Signaling 20item
  11. TGF-β / Smad Signaling 26item
  12. Angiogenesis 1 item
  13. GPCR/G protein 2item
  14. Stem Cell 6item
  15. Membrane Transporter/Ion Channel 3item
  16. Others 14item
  17. Immunology/Inflammation 1 item
Reversibility
  1. Reversible 21item
  2. Irreversible 5item
Target
  1. Cyclin-Dependent Kinases 21item
  2. Akt 1 item
  3. PI3K 12item
  4. Raf 7item
  5. Aurora Kinases 13item
  6. CSF-1R 2item
  7. mTOR 6item
  8. FLT3 8item
  9. GSK-3 7item
  10. PLK 4item
  11. Chk 5item
  12. Eph Receptors 3item
  13. VEGFR 19item
  14. PDGFR 14item
  15. c-Kit 6item
  16. RET 3item
  17. IRAK 2item
  18. Bromodomain-containing proteins(BRDs) 1 item
  19. p38 6item
  20. PKB 1 item
  21. JNK 2item
  22. SGK 2item
  23. Bcr-Abl 10item
  24. MEK 4item
  25. FGFR 6item
  26. Pim 4item
  27. Ribosomal s6 kinases (RSK) 1 item
  28. MET 5item
  29. Src 9item
  30. Trk Receptors 2item
  31. STAT 1 item
  32. EGFR 10item
  33. ROCK 6item
  34. BTK 1 item
  35. PAK 3item
  36. FAK 4item
  37. BMP and Other Activin Receptors 2item
  38. JAK 9item
  39. Syk 5item
  40. DNA-PK 3item
  41. AMPK 2item
  42. PDHK 1 item
  43. ErbB 2item
  44. S6 kinases 1 item
  45. Adenosine Kinases 2item
  46. ERK 2item
  47. c-MET 5item
  48. PKC 5item
  49. Ubiquitin-specific proteases 1 item
  50. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  51. Lyn 1 item
  52. HER2 2item
  53. Pyk2 3item
  54. LRRK2 3item
  55. Insulin and Insulin-like Receptors 2item
  56. ALK 3item
  57. ROS1 1 item
  58. Sphingosine kinases (SphKs) 1 item
  59. PKG 1 item
  60. PKA 1 item
  61. Myosin light chain kinases (MLCKs) 2item
  62. CaM-KK 1 item
  63. MELK 1 item
  64. Insulin-like growth factors (IGFs) 1 item
  65. Clk 1 item
  66. NUAK1 1 item
  67. NUAK2 1 item
  68. MK2 2item
  69. Fatty-acid-binding proteins (FABPs) 1 item
  70. Tie-2 2item
  71. RSK 1 item
  72. ATM/ATR 3item
  73. CK1 1 item
  74. Farnesyl Diphosphate Synthases 1 item
  75. CK2 3item
  76. HIPK2 1 item
  77. HIPK3 1 item
  78. P2X Receptors 1 item
  79. c-Fyn 1 item
  80. TAK1 1 item
  81. P110 1 item
  82. Hck 1 item
  83. Insulin Receptors 1 item
  84. IRG-1R 1 item
  85. eEF-2 1 item
  86. Cdc7 1 item
  87. ZAP-70 1 item
  88. c-RET 1 item
  89. p70 rsk 1 item
  90. TAM kinase 1 item
  91. AXL 1 item
  92. c-Fms tyrosine kinase 1 item
  93. STK 1 item
  94. MSK 1 item
  95. Lyn kinase 1 item
  96. ITK 1 item
  97. NUAK 1 item
  98. DCLK2 1 item
  99. Lck 1 item
  100. PKD 1 item
  101. tropomyosin receptor kinase 1 item
  102. SK 1 item
  103. ATM 1 item
  104. PIKfyve 1 item
  105. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 209item
  2. Cell Experiments 129item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 16item
  3. Adrenocortical Carcinoma 2item
  4. Advanced Renal Cell Carcinoma 1 item
  5. Bladder Cancer 4item
  6. Bladder Carcinoma 1 item
  7. B-lymphoid Malignancies 1 item
  8. Breast Cancer 43item
  9. Cancer 154item
  10. Cervical Cancer 4item
  11. Cholangiocarcinoma 2item
  12. Chronic Lymphocytic Leukemia 2item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 20item
  15. Colon Carcinoma 2item
  16. Colorectal Cancer 19item
  17. Diabetes 1 item
  18. Glioblastoma 17item
  19. Glioma 6item
  20. Hepatocellular Carcinoma 4item
  21. HIV Infections 1 item
  22. Immunological Diseases 1 item
  23. Inflammatory Bowel Disease 1 item
  24. Inflammatory Diseases 4item
  25. Leukemia 7item
  26. Liver Cancer 3item
  27. Lung Cancer 15item
  28. Lung Carcinoma 3item
  29. Lymphoma 9item
  30. Mantle Cell Lymphoma 1 item
  31. Melanoma 11item
  32. Multiple Myeloma 6item
  33. Myelofibrosis 1 item
  34. Myeloma 1 item
  35. Neuroblastoma 2item
  36. Non-small Cell Lung Cancer 5item
  37. Non-small Cell Lung Carcinoma 1 item
  38. Ovarian Cancer 14item
  39. Pancreatic Cancer 22item
  40. Prostate Cancer 17item
  41. Psoriasis 1 item
  42. Pulmonary Arterial Hypertension 1 item
  43. Renal Cancer 3item
  44. Renal Cell Carcinoma 5item
  45. Rheumatoid Arthritis 5item
  46. Thyroid Cancer 5item
  47. Type 2 Diabetes 3item