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  • Search results for: 'research area tyrosine kinase src'

Search results for: 'research area tyrosine kinase src'

Items 21-30 of 242

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  1. NVP-AEW541
    A2278 NVP-AEW541
    Target: Insulin Receptor
    Summary: IGF-IR inhibitor, novel, potent and selective
      ≥22 mg/mL
  2. Lapatinib
    A8218 Lapatinib
     2 Citation
    Target: ErbB
    Summary: EGFR/HER2 inhibitor,potent,selective and reversible
      ≥29.05 mg/mL
  3. Gefitinib (ZD1839)
    A8219 Gefitinib (ZD1839)
     3 Citation
    Target: EGFR
    Summary: Selective EGFR inhibitor
      ≥22.34 mg/mL
  4. AZD4547
    A8350 AZD4547
    Target: FGFR
    Summary: FGFR inhibitor
      ≥23.2 mg/mL
  5. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL
  6. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  7. BMS-754807
    A1185 BMS-754807
    Target: Insulin and Insulin-like Receptors
    Summary: IGF-1R/InsR inhibitor,potent and selective
      ≥23.05 mg/mL
  8. BMS-777607
    A5703 BMS-777607
    Target: MET
    Summary: C-Met inhibitor, potent and selective
      ≥25.65 mg/mL
  9. PRT062607 Hydrochloride
    A3736 PRT062607 Hydrochloride
     1 Citation
    Target: Syk
    Summary: SYK inhibitor,potent and selective
      ≥21.5 mg/mL
  10. Fenretinide
    A3412 Fenretinide
    Target: FAK
    Summary: Synthetic retinoid agonist
      insoluble in H2O; ≥19.6 mg/mL

Items 21-30 of 242

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Apoptosis 3item
  2. Chromatin/Epigenetics 24item
  3. Metabolism 1 item
  4. MAPK Signaling 20item
  5. Tyrosine Kinase 86item
  6. DNA Damage/DNA Repair 6item
  7. PI3K/Akt/mTOR Signaling 34item
  8. Cell Cycle/Checkpoint 54item
  9. Ubiquitination/ Proteasome 3item
  10. JAK/STAT Signaling 20item
  11. TGF-β / Smad Signaling 26item
  12. Angiogenesis 1 item
  13. GPCR/G protein 2item
  14. Stem Cell 6item
  15. Membrane Transporter/Ion Channel 3item
  16. Others 14item
  17. Immunology/Inflammation 1 item
Reversibility
  1. Reversible 21item
  2. Irreversible 5item
Target
  1. Cyclin-Dependent Kinases 21item
  2. Akt 1 item
  3. PI3K 12item
  4. Raf 7item
  5. Aurora Kinases 13item
  6. CSF-1R 2item
  7. mTOR 6item
  8. FLT3 8item
  9. GSK-3 7item
  10. PLK 4item
  11. Chk 5item
  12. Eph Receptors 3item
  13. VEGFR 19item
  14. PDGFR 14item
  15. c-Kit 6item
  16. RET 3item
  17. IRAK 2item
  18. Bromodomain-containing proteins(BRDs) 1 item
  19. p38 6item
  20. PKB 1 item
  21. JNK 2item
  22. SGK 2item
  23. Bcr-Abl 10item
  24. MEK 4item
  25. FGFR 6item
  26. Pim 4item
  27. Ribosomal s6 kinases (RSK) 1 item
  28. MET 5item
  29. Src 9item
  30. Trk Receptors 2item
  31. STAT 1 item
  32. EGFR 10item
  33. ROCK 6item
  34. BTK 1 item
  35. PAK 3item
  36. FAK 4item
  37. BMP and Other Activin Receptors 2item
  38. JAK 9item
  39. Syk 5item
  40. DNA-PK 3item
  41. AMPK 2item
  42. PDHK 1 item
  43. ErbB 2item
  44. S6 kinases 1 item
  45. Adenosine Kinases 2item
  46. ERK 2item
  47. c-MET 5item
  48. PKC 5item
  49. Ubiquitin-specific proteases 1 item
  50. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  51. Lyn 1 item
  52. HER2 2item
  53. Pyk2 3item
  54. LRRK2 3item
  55. Insulin and Insulin-like Receptors 2item
  56. ALK 3item
  57. ROS1 1 item
  58. Sphingosine kinases (SphKs) 1 item
  59. PKG 1 item
  60. PKA 1 item
  61. Myosin light chain kinases (MLCKs) 2item
  62. CaM-KK 1 item
  63. MELK 1 item
  64. Insulin-like growth factors (IGFs) 1 item
  65. Clk 1 item
  66. NUAK1 1 item
  67. NUAK2 1 item
  68. MK2 2item
  69. Fatty-acid-binding proteins (FABPs) 1 item
  70. Tie-2 2item
  71. RSK 1 item
  72. ATM/ATR 3item
  73. CK1 1 item
  74. Farnesyl Diphosphate Synthases 1 item
  75. CK2 3item
  76. HIPK2 1 item
  77. HIPK3 1 item
  78. P2X Receptors 1 item
  79. c-Fyn 1 item
  80. TAK1 1 item
  81. P110 1 item
  82. Hck 1 item
  83. Insulin Receptors 1 item
  84. IRG-1R 1 item
  85. eEF-2 1 item
  86. Cdc7 1 item
  87. ZAP-70 1 item
  88. c-RET 1 item
  89. p70 rsk 1 item
  90. TAM kinase 1 item
  91. AXL 1 item
  92. c-Fms tyrosine kinase 1 item
  93. STK 1 item
  94. MSK 1 item
  95. Lyn kinase 1 item
  96. ITK 1 item
  97. NUAK 1 item
  98. DCLK2 1 item
  99. Lck 1 item
  100. PKD 1 item
  101. tropomyosin receptor kinase 1 item
  102. SK 1 item
  103. ATM 1 item
  104. PIKfyve 1 item
  105. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 209item
  2. Cell Experiments 129item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 16item
  3. Adrenocortical Carcinoma 2item
  4. Advanced Renal Cell Carcinoma 1 item
  5. Bladder Cancer 4item
  6. Bladder Carcinoma 1 item
  7. B-lymphoid Malignancies 1 item
  8. Breast Cancer 43item
  9. Cancer 154item
  10. Cervical Cancer 4item
  11. Cholangiocarcinoma 2item
  12. Chronic Lymphocytic Leukemia 2item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 20item
  15. Colon Carcinoma 2item
  16. Colorectal Cancer 19item
  17. Diabetes 1 item
  18. Glioblastoma 17item
  19. Glioma 6item
  20. Hepatocellular Carcinoma 4item
  21. HIV Infections 1 item
  22. Immunological Diseases 1 item
  23. Inflammatory Bowel Disease 1 item
  24. Inflammatory Diseases 4item
  25. Leukemia 7item
  26. Liver Cancer 3item
  27. Lung Cancer 15item
  28. Lung Carcinoma 3item
  29. Lymphoma 9item
  30. Mantle Cell Lymphoma 1 item
  31. Melanoma 11item
  32. Multiple Myeloma 6item
  33. Myelofibrosis 1 item
  34. Myeloma 1 item
  35. Neuroblastoma 2item
  36. Non-small Cell Lung Cancer 5item
  37. Non-small Cell Lung Carcinoma 1 item
  38. Ovarian Cancer 14item
  39. Pancreatic Cancer 22item
  40. Prostate Cancer 17item
  41. Psoriasis 1 item
  42. Pulmonary Arterial Hypertension 1 item
  43. Renal Cancer 3item
  44. Renal Cell Carcinoma 5item
  45. Rheumatoid Arthritis 5item
  46. Thyroid Cancer 5item
  47. Type 2 Diabetes 3item