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Search results for: 'signal transduction'

Items 41-50 of 83

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  1. MK-2206 dihydrochloride
    A3010 MK-2206 dihydrochloride
     21 Citation
    Target: Akt
    Summary: Akt1/2/3 inhibitor
      insoluble in EtOH; ≥12.01 mg/mL
  2. BKM120
    A3015 BKM120
     1 Citation
    Target: PI3K
    Summary: Inhibitor of pan-Class I PI3K
      ≥20.52 mg/mL
  3. PLX-4720
    A3016 PLX-4720
     1 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥20.69 mg/mL
  4. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  5. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  6. BIX 02188
    A5803 BIX 02188
    Target: MEK
    Summary: MEK5 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL
  7. GF 109203X
    A8342 GF 109203X
     1 Citation
    Target: PKC
    Summary: Protein kinase C,MLCK,PKG and PKA inhibitor
      insoluble in EtOH; insoluble in H2O; ≥20.6 mg/mL
  8. LY2090314
    A3570 LY2090314
    Target: GSK-3
    Summary: Potent GSK-3 inhibitor
      insoluble in H2O; ≥91 mg/mL
  9. Vemurafenib (PLX4032, RG7204)
    A3004 Vemurafenib (PLX4032, RG7204)
     9 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥24.5 mg/mL
  10. CAL-101 (Idelalisib, GS-1101)
    A3005 CAL-101 (Idelalisib, GS-1101)
     2 Citation
    Target: PI3K
    Summary: PI3K inhibitor

Items 41-50 of 83

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Category
  1. Proteases 3item
  2. Apoptosis 3item
  3. Chromatin/Epigenetics 3item
  4. Metabolism 3item
  5. MAPK Signaling 13item
  6. Tyrosine Kinase 4item
  7. DNA Damage/DNA Repair 2item
  8. PI3K/Akt/mTOR Signaling 26item
  9. Cell Cycle/Checkpoint 1 item
  10. JAK/STAT Signaling 7item
  11. TGF-β / Smad Signaling 7item
  12. Stem Cell 9item
  13. Membrane Transporter/Ion Channel 1 item
  14. Cancer Biology 3item
  15. Endocrinology and Hormones 2item
  16. Neuroscience 7item
  17. Obesity, Appetite Control & Diabetes 1 item
  18. Other Signal Transduction 7item
  19. Others 2item
  20. Immunology/Inflammation 1 item
  21. Cardiovascular 5item
Specificity
  1. Selective 48item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Akt 7item
  3. PI3K 11item
  4. Raf 6item
  5. mTOR 6item
  6. Androgen Receptors 1 item
  7. GSK-3 4item
  8. VEGFR 3item
  9. PDGFR 1 item
  10. Phosphodiesterases (PDEs) 1 item
  11. p38 4item
  12. PKB 1 item
  13. MEK 3item
  14. PORCN 1 item
  15. FGFR 1 item
  16. GABAB Receptors 1 item
  17. NMDA Receptors 1 item
  18. STAT 4item
  19. EGFR 1 item
  20. JAK 3item
  21. DNA-PK 1 item
  22. HSP90 1 item
  23. Toll-like receptors (TLRs) 1 item
  24. ERK 2item
  25. PKC 5item
  26. ALK 1 item
  27. PKG 1 item
  28. PKA 3item
  29. RSK 1 item
  30. NO Donors / Precursors 1 item
  31. IL Receptors 1 item
  32. AChE 1 item
  33. BACE 1 item
  34. p70 rsk 1 item
  35. sodium channels 1 item
  36. Smoothened receptor 1 item
  37. Nrf2/ARE signal 1 item
  38. PPAR 1 item
  39. Antibiotic 1 item
  40. Prk 1 item
  41. ICAM 1 item
  42. Rho 1 item
  43. Thrombin Receptor 1 item
  44. prolactin secretion 1 item
  45. gonadotropin release 1 item
  46. FKBP 1 item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 1 item
  4. Breast Cancer 13item
  5. Cancer 46item
  6. Cervical Cancer 1 item
  7. Colon Cancer 6item
  8. Colorectal Cancer 6item
  9. Glioblastoma 8item
  10. Glioma 3item
  11. Heart Failure 1 item
  12. Leukemia 6item
  13. Liver Cancer 1 item
  14. Lung Cancer 3item
  15. Lymphoma 2item
  16. Melanoma 5item
  17. Multiple Myeloma 1 item
  18. Myeloma 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 4item
  21. Ovarian Cancer 5item
  22. Pancreatic Cancer 5item
  23. Pancreatic Carcinoma 1 item
  24. Prostate Cancer 7item
  25. Pulmonary Fibrosis 1 item
  26. Rheumatoid Arthritis 2item
  27. Thyroid Cancer 2item
  28. Type 2 Diabetes 1 item