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  • Search results for: 'signal transduction'

Search results for: 'signal transduction'

Items 1-10 of 75

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  1. Endomorphin-1
    A1013 Endomorphin-1
    Summary: Agonist of μopioid receptors,highly potent and selective
      ≥14.9 mg/mL
  2. Agouti-related Protein (AGRP) (25-82), human
    A1134 Agouti-related Protein (AGRP) (25-82), human
    Target: Melanocortin (MC) Receptors
    Summary: Agouti-related peptide(25-82)
      insoluble in EtOH; insoluble in DMSO; ≥100 mg/mL
  3. Cucurbitacin I
    A4512 Cucurbitacin I
    Target: STAT|JAK
    Summary: STAT3/JAK2 signaling inhibitor
      ≥22.45 mg/mL
  4. Wnt-C59
    A8685 Wnt-C59
     2 Citation
    Target: PORCN
    Summary: PORCN inhibitor,highly potent and selective
      .95 mg/mL
      insoluble in H2O; ≥18
  5. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
  6. SB 203580
    A8254 SB 203580
     9 Citation
    Target: p38|PKB
    Summary: P38 MAP kinase inhibitor
      insoluble in H2O; ≥18.872 mg/mL
  7. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  8. PD184352 (CI-1040)
    A1792 PD184352 (CI-1040)
    Target: MEK
    Summary: Selective MEK inhibitor
      ≥47.9 mg/mL
  9. SB202190 (FHPI)
    A1632 SB202190 (FHPI)
     5 Citation
    Target: p38
    Summary: P38 MAPK inhibitor
  10. U0126-EtOH
    A1337 U0126-EtOH
     10 Citation
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.33 mg/mL

Items 1-10 of 75

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Proteases 2item
  2. Chromatin/Epigenetics 3item
  3. Metabolism 2item
  4. MAPK Signaling 16item
  5. Tyrosine Kinase 9item
  6. DNA Damage/DNA Repair 2item
  7. PI3K/Akt/mTOR Signaling 24item
  8. Ubiquitination/ Proteasome 1 item
  9. JAK/STAT Signaling 8item
  10. TGF-β / Smad Signaling 11item
  11. Stem Cell 11item
  12. Membrane Transporter/Ion Channel 1 item
  13. Endocrinology and Hormones 1 item
  14. Neuroscience 3item
  15. Obesity, Appetite Control & Diabetes 2item
  16. Other Signal Transduction 2item
  17. Immunology/Inflammation 1 item
  18. Cardiovascular 1 item
Reversibility
  1. Reversible 3item
  2. Irreversible 1 item
Target
  1. Akt 4item
  2. PI3K 10item
  3. Raf 6item
  4. mTOR 6item
  5. Androgen Receptors 1 item
  6. GSK-3 5item
  7. P-glycoprotein (P-gp) 1 item
  8. VEGFR 3item
  9. PDGFR 1 item
  10. Phosphodiesterases (PDEs) 1 item
  11. p38 4item
  12. PKB 1 item
  13. JNK 2item
  14. MEK 4item
  15. PORCN 1 item
  16. FGFR 1 item
  17. GABAB Receptors 1 item
  18. Smoothened 1 item
  19. STAT 4item
  20. EGFR 2item
  21. Hedgehog 1 item
  22. BMP and Other Activin Receptors 2item
  23. JAK 2item
  24. Syk 1 item
  25. HSP90 1 item
  26. TNKS 1 item
  27. Toll-like receptors (TLRs) 1 item
  28. ERK 1 item
  29. PKC 3item
  30. Melanocortin (MC) Receptors 1 item
  31. NO Donors / Precursors 1 item
  32. IL Receptors 1 item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 1 item
  4. Breast Cancer 18item
  5. Cancer 53item
  6. Cervical Cancer 2item
  7. Colon Cancer 8item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 9item
  10. Glioblastoma 10item
  11. Glioma 3item
  12. Leukemia 5item
  13. Liver Cancer 1 item
  14. Lung Cancer 6item
  15. Lymphoma 2item
  16. Melanoma 5item
  17. Multiple Myeloma 1 item
  18. Myeloma 1 item
  19. Neuroblastoma 2item
  20. Non-small Cell Lung Cancer 5item
  21. Ovarian Cancer 6item
  22. Pancreatic Cancer 7item
  23. Pancreatic Carcinoma 2item
  24. Prostate Cancer 10item
  25. Pulmonary Arterial Hypertension 1 item
  26. Pulmonary Fibrosis 1 item
  27. Renal Cancer 1 item
  28. Rheumatoid Arthritis 2item
  29. Thyroid Cancer 2item
  30. Type 2 Diabetes 1 item