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Signaling Pathways

Items 51-60 of 80

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  1. Lopinavir
    A8204 Lopinavir
    Summary: HIV protease inhibitor,highly potent
      ≥31.45 mg/mL
  2. VX-222 (VCH-222, Lomibuvir)
    A4032 VX-222 (VCH-222, Lomibuvir)
    Target: HCV polymerase
    Summary: NNI of HCV RNA polymerase
      ≥44.6 mg/mL
  3. Glimepiride
    A4033 Glimepiride
    Target: Inward Rectifier Potassium (Kir) Channels
    Summary: Sulfonylurea compound
      ≥21.45 mg/mL
  4. Sitagliptin phosphate monohydrate
    A4036 Sitagliptin phosphate monohydrate
     5 Citation
    Target: DPP-4
    Summary: Potent DPP-4 inhibitor
      ≥23.8 mg/mL
  5. MG-132
    A2585 MG-132
     26 Citation
    Target: Proteasome
    Summary: Proteasome inhibitor, Cell permeable, reversible
      ≥23.78 mg/mL
  6. Alogliptin (SYR-322)
    A4038 Alogliptin (SYR-322)
     1 Citation
    Target: DPP-4
    Summary: DPP-4 inhibitor,potent and highly selective
  7. Atazanavir
    A8205 Atazanavir
     1 Citation
    Summary: HIV protease inhibitor,highly potent
      ≥28.6 mg/mL
  8. Amprenavir (agenerase)
    A8201 Amprenavir (agenerase)
    Summary: HIV-1 protease inhibitor
  9. Marimastat
    A4049 Marimastat
     1 Citation
    Target: MMP
    Summary: MMPs inhibitor,board spectrum
      ≥2.8 mg/mL
  10. GM 6001
    A4050 GM 6001
     2 Citation
    Target: MMP
    Summary: Broad spectrum MMP inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.42 mg/mL

Items 51-60 of 80

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  1. Caspase 10item
  2. Aminopeptidase 2item
  3. Calpains 5item
  4. Cathepsin 8item
  5. DPP-4 5item
  6. Elastase 3item
  7. Gamma Secretase 8item
  8. HCV Protease 6item
  9. HSP 13item
  10. HIV Integrase 2item
  11. HIV Protease 5item
  12. MMP 7item
  13. Serine Protease 2item
  14. Thrombin 5item
  15. Other Proteases 2item
Reversibility
  1. Reversible 13item
  2. Irreversible 7item
Target
  1. Caspases 10item
  2. Proteasome 1 item
  3. Cathepsins 11item
  4. MMP 6item
  5. Factor Xa 2item
  6. Thymidylate Synthase 1 item
  7. Aminopeptidases 2item
  8. HSP90 10item
  9. Notch 1 item
  10. thrombin 1 item
  11. Renin 1 item
  12. HIV proteases 1 item
  13. Pepsins 1 item
  14. Calpains 5item
  15. HCV Proteases 3item
  16. Trypsins 1 item
  17. Trypsin 1 item
  18. Chymotrypsin 1 item
  19. Kallikrein 1 item
  20. Trypsinogen 1 item
  21. HIV-1 gp120 1 item
  22. HIV Integrases 1 item
  23. Inward Rectifier Potassium (Kir) Channels 1 item
  24. Papains 1 item
  25. DPP-4 4item
  26. Nonstructural protein 5B (NS5B) 1 item
  27. ADAMs 1 item
  28. Dipeptidyl-peptidase II 1 item
  29. HCV polymerase 2item
  30. Elastases 1 item
  31. NE 1 item
Reported Experiments
  1. Animal Experiments 70item
  2. Cell Experiments 49item
Related Disease
  1. Acute Lung Injury 1 item
  2. Acute Myeloid Leukemia 1 item
  3. Breast Cancer 11item
  4. Cancer 31item
  5. Chronic Lymphocytic Leukemia 1 item
  6. Clear Cell Renal Cell Carcinoma 1 item
  7. Colon Cancer 2item
  8. Diabetes 2item
  9. Glioma 1 item
  10. HCV 3item
  11. Hepatitis C 3item
  12. HIV 1 item
  13. HIV Infections 2item
  14. Inflammatory Diseases 1 item
  15. Lung Cancer 3item
  16. Lymphoma 1 item
  17. Melanoma 7item
  18. Multiple Myeloma 2item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 2item
  21. Osteoporosis 1 item
  22. Ovarian Cancer 4item
  23. Pancreatic Cancer 3item
  24. Prostate Cancer 3item
  25. Psoriasis 1 item
  26. Renal Cell Carcinoma 1 item
  27. Rheumatoid Arthritis 3item
  28. Squamous Cell Carcinoma 1 item
  29. Type 2 Diabetes 1 item