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Signaling Pathways

Items 71-80 of 80

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  1. CA 074
    A1926 CA 074
     2 Citation
    Target: Cathepsins
    Summary: Cathepsin B inhibitor
      ≥19.17 mg/mL
  2. Q-VD(OMe)-OPh
    A8165 Q-VD(OMe)-OPh
     6 Citation
    Target: Caspases
    Summary: Pan-caspase inhibitor
      ≥26.35 mg/mL
  3. 5-R-Rivaroxaban
    A3126 5-R-Rivaroxaban
    Target: Factor Xa
    Summary: Factor Xa (FXa) inhibitor
      ≥20.85 mg/mL
  4. Bivalirudin Trifluoroacetate
    A3244 Bivalirudin Trifluoroacetate
    Target: thrombin
    Summary: Reversible thrombin inhibitor
      ≥54.5 mg/mL
  5. BMS-626529
    A3253 BMS-626529
     2 Citation
    Target: HIV-1 gp120
    Summary: HIV-1 attachment inhibitor
      insoluble in H2O; insoluble in EtOH; ≥1.48 mg/mL
  6. UAMC 00039 dihydrochloride
    B5780 UAMC 00039 dihydrochloride
    Target: Dipeptidyl-peptidase II
    Summary: dipeptidyl peptidase II (DPP-II) inhibitor
      ≥133.6 mg/mL
  7. Gedunin
    B7393 Gedunin
    Target: HSP90
    Summary: naturally occurring Hsp90 inhibitor
      Soluble in DMSO
  8. HSP990 (NVP-HSP990)
    B4797 HSP990 (NVP-HSP990)
    Target: HSP90
    Summary: Hsp90 inhibitor, potent and selective
      insoluble in H2O; insoluble in EtOH; ≥12.3 mg/mL
  9. EC 144
    B4920 EC 144
    Target: HSP90
    Summary: High affinity, potent and selective Hsp90 inhibitor
      <41.39 mg/mL
  10. TAPI-1
    B4686 TAPI-1
     2 Citation
    Target: MMP
    Summary: TACE/ADAM17 inhibitor
      ≥24.98 mg/mL

Items 71-80 of 80

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Category
  1. Caspase 10item
  2. Aminopeptidase 2item
  3. Calpains 5item
  4. Cathepsin 8item
  5. DPP-4 5item
  6. Elastase 3item
  7. Gamma Secretase 8item
  8. HCV Protease 6item
  9. HSP 13item
  10. HIV Integrase 2item
  11. HIV Protease 5item
  12. MMP 7item
  13. Serine Protease 2item
  14. Thrombin 5item
  15. Other Proteases 2item
Reversibility
  1. Reversible 13item
  2. Irreversible 7item
Target
  1. Caspases 10item
  2. Proteasome 1 item
  3. Cathepsins 11item
  4. MMP 6item
  5. Factor Xa 2item
  6. Thymidylate Synthase 1 item
  7. Aminopeptidases 2item
  8. HSP90 10item
  9. Notch 1 item
  10. thrombin 1 item
  11. Renin 1 item
  12. HIV proteases 1 item
  13. Pepsins 1 item
  14. Calpains 5item
  15. HCV Proteases 3item
  16. Trypsins 1 item
  17. Trypsin 1 item
  18. Chymotrypsin 1 item
  19. Kallikrein 1 item
  20. Trypsinogen 1 item
  21. HIV-1 gp120 1 item
  22. HIV Integrases 1 item
  23. Inward Rectifier Potassium (Kir) Channels 1 item
  24. Papains 1 item
  25. DPP-4 4item
  26. Nonstructural protein 5B (NS5B) 1 item
  27. ADAMs 1 item
  28. Dipeptidyl-peptidase II 1 item
  29. HCV polymerase 2item
  30. Elastases 1 item
  31. NE 1 item
Reported Experiments
  1. Animal Experiments 70item
  2. Cell Experiments 49item
Related Disease
  1. Acute Lung Injury 1 item
  2. Acute Myeloid Leukemia 1 item
  3. Breast Cancer 11item
  4. Cancer 31item
  5. Chronic Lymphocytic Leukemia 1 item
  6. Clear Cell Renal Cell Carcinoma 1 item
  7. Colon Cancer 2item
  8. Diabetes 2item
  9. Glioma 1 item
  10. HCV 3item
  11. Hepatitis C 3item
  12. HIV 1 item
  13. HIV Infections 2item
  14. Inflammatory Diseases 1 item
  15. Lung Cancer 3item
  16. Lymphoma 1 item
  17. Melanoma 7item
  18. Multiple Myeloma 2item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 2item
  21. Osteoporosis 1 item
  22. Ovarian Cancer 4item
  23. Pancreatic Cancer 3item
  24. Prostate Cancer 3item
  25. Psoriasis 1 item
  26. Renal Cell Carcinoma 1 item
  27. Rheumatoid Arthritis 3item
  28. Squamous Cell Carcinoma 1 item
  29. Type 2 Diabetes 1 item