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Signaling Pathways

Signaling Pathways

A3847 SU5416

Target: VEGFR

Summary: VEGF receptor inhibitor and AHR agonist

insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
B1438 BMS-794833

Target: MET|Flk-1

Summary: Met/VEGFR-2 inhibitor,potent and ATP-competitive

≥23.45 mg/mL
A3020 (R)-Crizotinib

2 Citation

Target: c-MET

Summary: C-MET/ALK inhibitor,potent and ATP-competitve

insoluble in H2O; insoluble in EtOH; ≥7.51 mg/mL
B5832 Altiratinib

1 Citation

Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2

Summary: c-MET/TIE-2/VEGFR inhibitor

≥21.55 mg/mL