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Signaling Pathways

Items 41-50 of 55

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  1. Pazopanib (GW-786034)
    A3022 Pazopanib (GW-786034)
    Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL
  2. BFH772
    B6199 BFH772
    Summary: VEGFR2 inhibitor
      ≥53.4 mg/mL
  3. BAW2881 (NVP-BAW2881)
    B7800 BAW2881 (NVP-BAW2881)
    Summary: VEGFR inhibitor
      ≥42.4 mg/mL
  4. MAZ51
    C3342 MAZ51
    Target: VEGFR
    Summary: VEGFR3 antagonist
      insoluble in EtOH; insoluble in H2O; ≥31.4 mg/mL
  5. Tivozanib (hydrate)
    C3415 Tivozanib (hydrate)
    Summary: VEGFR inhibitor, orally available
      ≤25 mg/mL
  6. AZD2932
    B5835 AZD2932
    Target: FLT3|VEGFR|PDGFR|c-Kit
    Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit
      Soluble in DMSO
  7. Fruquintinib(HMPL-013)
    B5864 Fruquintinib(HMPL-013)
    Target: VEGFR
    Summary: Potent and selective inhibitor of VEGFR 1, 2, 3
      insoluble in H2O; insoluble in EtOH; ≥6.35 mg/mL
  8. Dovitinib (TKI258) Lactate
    B5953 Dovitinib (TKI258) Lactate
    Target: CSF-1R|FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).
      insoluble in EtOH; ≥10.62 mg/mL
  9. AAL-993
    C3730 AAL-993
    Summary: VEGF receptors inhibitor
      ≤1 mg/mL
  10. VEGFR Tyrosine Kinase Inhibitor II
    C4603 VEGFR Tyrosine Kinase Inhibitor II
     1 Citation
    Summary: VEGFR inhibitor
      ≤25 mg/mL

Items 41-50 of 55

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