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Signaling Pathways

Signaling Pathways

A2197 Dacarbazine

Target: DNA Alkylating

Summary: Antineoplastic( malignant melanoma and sarcomas)

insoluble in EtOH; ≥0.54 mg/mL
A2097 Ifosfamide

Target: DNA Alkylating

Summary: Cytostatic agent

≥13.05 mg/mL
A2451 Epirubicin HCl

Target: Topoisomerases

Summary: Antibiotic antitumor agent

≥29.00 mg/mL
A5424 Fludarabine

Summary: DNA synthsis inhibitor

insoluble in H2O; insoluble in EtOH; ≥9.25 mg/mL
A1769 KU-0060648

1 Citation

Target: PI3K|DNA-PK

Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
A8315 NU7441 (KU-57788)

4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8331 Bleomycin Sulfate

1 Citation

Summary: Chemotherapy agent, induces DNA strand break

≥125 mg/mL
A8336 KU-60019

2 Citation

Target: ATM/ATR

Summary: ATM kinase inhibitor,potent and selective

≥27.4 mg/mL
A8437 Gemcitabine

1 Citation

Summary: inhibitor of DNA synthesis

≥11.75 mg/mL
A8547 Tubastatin A HCl

1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC6 inhibitor,potent and selective

insoluble in EtOH; ≥12.34 mg/mL