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Signaling Pathways

Signaling Pathways

A8178 Panobinostat (LBH589)

10 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.47 mg/mL
A8183 Trichostatin A (TSA)

13 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in H2O; ≥15.12 mg/mL
A8173 Romidepsin (FK228, depsipeptide)

7 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC1/HDAC2 inhibitor, potent and selective

≥27.04 mg/mL
A8176 Apicidin

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

soluble in DMSO or ethanol
N1315 Parthenolide

Target: Histone Deacetylases (HDACs)|MDM2|DNA Methyltransferases|p53|5-HT
A4083 Rocilinostat (ACY-1215)

1 Citation

Target: Histone Deacetylases (HDACs)

Summary: Selective HDAC6 inhibitor

≥21.675 mg/mL
A4084 Vorinostat (SAHA, MK0683)

9 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
A4089 Mocetinostat (MGCD0103, MG0103)

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,isotype-selective and potent

insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
A4090 JNJ-26481585

3 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
A4091 PCI-34051

1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC8 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL