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Signaling Pathways

Items 11-20 of 27

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  1. Tyrphostin AG 1296
    A2477 Tyrphostin AG 1296
     1 Citation
    Target: PDGFR
    Summary: PDGFR inhibitor,selective and ATP-competitive
  2. Crenolanib (CP-868596)
    A8307 Crenolanib (CP-868596)
     1 Citation
    Target: FLT3|PDGFR
    Summary: PDGFR-β inhibitor,potent and selective
      ≥22.2 mg/mL
  3. Axitinib (AG 013736)
    A8370 Axitinib (AG 013736)
     1 Citation
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR1/ c-Kit inhibitor
      insoluble in H2O; ≥19.3 mg/mL
  4. MK-2461
    A8476 MK-2461
    Target: FLT3|PDGFR|MET|Ron
    Summary: C-Met (WT/mutants) inhibitor
      ≥24.8 mg/mL
  5. CHIR-124
    A8394 CHIR-124
    Target: FLT3|GSK-3|Chk|PDGFR
    Summary: Chk1 inhibitor,novel and potent
      insoluble in H2O; ≥10.5 mg/mL
  6. Telatinib (BAY 57-9352)
    A8550 Telatinib (BAY 57-9352)
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR-2/-3,PDGFR-β and c-Kit inhibitor
      insoluble in H2O; insoluble in EtOH; ≥20.5 mg/mL
  7. PP121
    B2172 PP121
    Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck
    Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
  8. CP-673451
    B2173 CP-673451
    Target: PDGFR
    Summary: PDGFRα/β inhibitor,potent and selective
  9. Regorafenib hydrochloride
    A3750 Regorafenib hydrochloride
    Target: Raf|VEGFR|PDGFR|c-Kit|c-RET
    Summary: Tyrosine kinase inhibitor
      ≥25.95 mg/mL
  10. SU 5402
    A3843 SU 5402
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR2/FGFR/PDGFR/EGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL

Items 11-20 of 27

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