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Signaling Pathways

Signaling Pathways

A8617 CCT128930 HCl

Target: Akt

Summary: AKT inhibitor

insoluble in H2O; ≥17.1 mg/mL
A8620 AZD-3463

3 Citation

Target: ALK|Insulin-like growth factors (IGFs)

Summary: ALK/IGF1R inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.22 mg/mL
A8621 Bestatin hydrochloride

Target: Aminopeptidases

Summary: Inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.

≥125 mg/mL
A8623 TOK-001

Target: Androgen Receptors|Cytochrome P450 (CYP450)

Summary: CYP17 inhibitor and androgen receptor (AR) antagonist

insoluble in H2O; ≥12.4 mg/mL
A8628 Chloroquine diphosphate

1 Citation

Target: Autophagy

Summary: Antimalarial drug,TLR7 TLR9 inhibitor

insoluble in DMSO; insoluble in EtOH; ≥106.06 mg/mL
A8631 FK 866 hydrochloride

Target: NMPRTase

Summary: NMPRTase inhibitor

≥18.95 mg/mL
A8637 IOWH-032

Target: CFTR

Summary: CFTR inhibitor

≥21.85 mg/mL
A8641 LEE011

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
A8642 R547

2 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK1/2/4 inhibitor,ATP-competitive

Soluble in DMSO
A8644 Acyclovir

Target: HSV

Summary: Antiviral agent

insoluble in H2O; insoluble in EtOH; ≥11.4 mg/mL