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Signaling Pathways

Signaling Pathways

B3252 Dorsomorphin (Compound C)

5 Citation

Target: AMPK

Summary: AMPK inhibitor

insoluble in H2O; insoluble in EtOH; ≥8.49 mg/mL
B3277 AMG 925

Target: Cyclin-Dependent Kinases|FLT3

Summary: FLT3/CDK4 inhibitor,potent and selective

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B3283 PF-04449913

Target: Smoothened

Summary: Antagonist of smoothened

≥20.15 mg/mL
B1437 PF-477736

Target: Chk

Summary: Chk1 inhibitor

insoluble in EtOH; insoluble in H2O; ≥5.24 mg/mL
B1642 WYE-125132 (WYE-132)

Target: mTOR

Summary: ATP-competitive mTOR inhibitor, highly potent

insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
B1285 SB 203580 hydrochloride

Target: p38

Summary: Specific p38-MAPKs inhibitor

insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL
B2206 PD123319

Target: Angiotensin AT2 Receptors

Summary: Angiotensin AT2 receptor antagonist

≥22.4 mg/mL
B2172 PP121

Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck

Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
B2227 BI-D1870

1 Citation

Target: p90 S6K

Summary: P90 RSK inhibitor,ATP-competitive and cell-permeable

insoluble in H2O; ≥19.55 mg/mL
B1405 GW5074

Summary: C-Raf inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥21.9 mg/mL