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Signaling Pathways

Signaling Pathways

A3423 Galanthamine

2 Citation

Target: AChE

Summary: Acetylcholinesterase inhibitor

≥14.37 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A3440 Glyoxalase I inhibitor

Target: Glyoxalase I

Summary: Glyoxalase I inhibitor

Soluble in DMSO
A3444 GS-9620

Target: Toll-like receptors (TLRs)

Summary: TLR-7 agonist

insoluble in H2O; ≥20.55 mg/mL
A3446 GSK126

5 Citation

Target: EZH2

Summary: EZH2 inhibitor

insoluble in H2O; insoluble in EtOH; ≥4.38 mg/mL
A3448 GSK2606414

4 Citation

Summary: PERK inhibitor,potent and selective

≥22.57 mg/mL
A3453 GW1929

Target: PPAR

Summary: Potent PPARγ agonist

≥ 35 mg/mL
A3454 GW3965

1 Citation

Target: Liver X receptors (LXRs)

Summary: HLXRα/hLXRβ agonist,potent and selective

Soluble in DMSO
A3478 Hydroxyfasudil

Target: ROCK|Rho-kinase

Summary: Rho-kinase inhibitor and vasodilator

Soluble in DMSO
A3485 IKK-2 inhibitor VIII

Summary: IKK-2 inhibitor,potent and selective

Soluble in DMSO