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Signaling Pathways

Signaling Pathways

B3704 Nexturastat A

Target: Histone Deacetylases (HDACs)

Summary: HDAC6 inhibitor,highly potent and selective

insoluble in H2O; ≥16.3 mg/mL
B3707 ML167

Target: Clk

Summary: Clk4 inhibitor,highly selective

insoluble in EtOH; insoluble in H2O; ≥16.75 mg/mL
B3708 RGD (Arg-Gly-Asp) Peptides

1 Citation

Target: Integrin-ligand interactions

Summary: Inhibits integrin binding to RGD motifs

insoluble in DMSO; insoluble in EtOH; ≥17.3 mg/mL
B3742 Thio-TEPA

Summary: alkylating agent used to treat cancer
B3941 Talabostat mesylate

2 Citation

Target: DPP-4

Summary: orally active, specific inhibitor of DPP4

≥11.45 mg/mL
B4094 NMS-1286937

Target: PLK

Summary: PLK1 inhibitor, orally bioavailable

insoluble in H2O; insoluble in EtOH; ≥13.33 mg/mL
B4633 GNE0877

Target: LRRK2

Summary: Potent and selective LRRK2 inhibitor

≥21 mg/mL
A3872 TH-302

Summary: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth

≥22.45 mg/mL
A3875 Tipiracil hydrochloride

Target: Thymidine Phosphorylases

Summary: Thymidine phosphorylase inhibitor

insoluble in DMSO; insoluble in EtOH; ≥13.25 mg/mL
A3885 Tozadenant

Target: Adenosine A2A Receptors

Summary: Adenosine 2a receptor antagonist,novel and selective

insoluble in EtOH; insoluble in H2O; ≥20.35 mg/mL