CETP Inhibitor Drug Screening Kit (Fluorometric)

Cholesteryl ester transfer protein (CETP) is a plasma protein that transfers a cholesteryl ester from high-density lipoproteins (HDL) to low-density lipoproteins (LDL) or very-low-density lipoproteins (VLDL) in exchange for a triglyceride, and vice versa. HDL plays important roles in lipid metabolism and cardiovascular health. HDL transports cholesterol to steroidogenic tissues for steroid synthesis or to the liver for excretion. HDL is also involved in the reverse cholesterol transport pathway, protecting against atherosclerosis by removing cholesterol from lipid-filled macrophages. CETP is known as a target to increase HDL.

The CETP Inhibitor Drug Screening Kit (Fluorometric) provides a sensitive, simple and convenient way for screening of CETP inhibitors in various biological fluids based on fluorometric method. The kit contains human CETP enzyme and CETP Inhibitor Anacetrapib, which provide convenience for ultimate user.