Cy3.5 hydrazide (non-sulfonated)
Catalog No.
A8266
carbonyl-reactive dye
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Cy3.5 hydrazide is a near infrared fluorophore that can react with various carbonyl groups in biomolecules which are generated after oxidative stress or deamination of proteins. In addition, aldehyde moieties can be produced by periodate oxidation of sugar residues of glycoproteins, such as antibodies that can then be oxidized by sodium periodate and labeled with Cy3.5 hydrazide to form Cy3. 5 labeled antibodies. For biomolecule labeling, the labeling regent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 643.69 |
| Cas No. | N/A |
| Formula | C38H44Cl2N4O |
| Solubility | ≥64.4 mg/mL in DMSO; insoluble in H2O; ≥33.33 mg/mL in EtOH with ultrasonic |
| Chemical Name | 3-(6-hydrazinyl-6-oxohexyl)-1,1-dimethyl-2-((1E,3E)-3-(1,1,3-trimethyl-1H-benzo[e]indol-2(3H)-ylidene)prop-1-en-1-yl)-1H-benzo[e]indol-3-ium chloride hydrochloride |
| SDF | Download SDF |
| Canonical SMILES | CN1C2=CC=C3C=CC=CC3=C2C(C)(C)/C1=C\C=C\C4=[N+](CCCCCC(NN)=O)C5=CC=C(C=CC=C6)C6=C5C4(C)C.Cl.[Cl-] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| Excitation max (nm) | 591 | Emission max (nm) | 604 |
| Extinction Coefficient (M-1cm-1) | 116000 | Quantum Yield | 0.35 |
| CF260 | 0.29 | CF280 | 0.22 |
Quality Control & MSDS
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Chemical structure
