DiscoveryProbe™ Tyrosine Kinase Inhibitor Library
Catalog No.
L1028
A unique collection of 369 tyrosine kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).
Featured Products
| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
| A1389 | WZ4002 | Mutant-selective EGFR inhibitor(L858R,T790M), irreversible and potent | EGFR | 1213269-23-8 | CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl)OC |
| A2838 | OSI-930 | Inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck | c-Kit | 728033-96-3 | C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F |
| A3014 | BGJ398 | FGFR inhibitor ,potent and selective | FGFR | 872511-34-7 | CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl |
| A5092 | JNJ-38877605 | C-Met inhibitor,ATP-competitive | c-MET | 943540-75-8 | CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2 |
| A8324 | LDN-193189 | ALK inhibitor,potent and selective | SMAD | 1062368-24-4 | C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3 |
| A8329 | R428 | Selective Axl inhibitor | Axl | 1037624-75-1 | C1CCN(C1)C2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76 |
| A8528 | TAK-285 | HER2/EGFR(HER1) inhibitor | HER2 | 871026-44-7 | CC(C)(CC(=O)NCCN1C=CC2=C1C(=NC=N2)NC3=CC(=C(C=C3)OC4=CC=CC(=C4)C(F)(F)F)Cl)O |
| A8696 | FIIN-2 | Irreversible inhibitor of FGFR | EGFR | 1633044-56-0 | O=C(C=C)NC1=CC=C(CN2C(N(C3=CC(OC)=CC(OC)=C3)CC4=CN=C(NC5=CC=C(N6CCN(C)CC6)C=C5)N=C42)=O)C=C1 |
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
| Form | Pre-dissolved DMSO solutions | Stability | Solution: -20°C for 12 months, -80°C for 24 months |
| Packaging | 96-well rack with Matrix 2D Barcoded ScrewTop Storage tubes (250 μL or 100 μL/well, 10 mM DMSO). 96-well DeepWell format with peelable foil seal and EVA cap (100 μL/well, 10 mM DMSO). |
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| Shipping Condition | Evaluation sample solution: ship with blue ice All other available size: ship with RT, or blue ice upon request |
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-- Available in stock with overnight delivery and free shipping over $500.
-- Cost-effective and competitive price to save your budget.
-- Potent, selective and cell-permeable in inhibiting or activating target molecules.
-- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
-- Detailed files describing potency, selectivity and applications etc.
-- Supported by published data from top peer-reviewed journals.
-- Guaranteed high quality with NMR and HPLC validation.
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