ER-Tracker Green is a green-fluorescent endoplasmic reticulum (ER) probe that selectively labels ER of live cells. ER-Tracker Green is the BODIPY FL labeled glibenclamide. Glibenclamide, a drug for diabetic patients, specially binds to the sulphonylurea receptors of ATP-sensitive K+ channels on ER. So fluorescent-labeled glibenclamide (ER-Tracker Green) can label ER. Unlike conventional ER probe DiOC6(3), ER-Tracker Green does not appear to be toxic to cells at low concentrations, while it is highly selective for ER and rarely stains mitochondria. ER-Tracker Green stains live cells well but is not well-retained after fixation with formaldehyde. Glibenclamide may affect ER function, and variable expression of sulphonylurea receptors in some special cell types may lead to non-ER labeling. This reagent is provided as a 1 mM solution in DMSO.
Properties
Ex/Em
504/511
Storage
The product should be stored at -20°C away from light and moisture.
Shipping Condition
Blue ice
EXP Date
This product should be stored at -20°C away from light and moisture. Avoid repeated freeze/thaw cycles, stable for 6 months.
Chemical Properties
Physical Appearance
Liquid
M.Wt
783.09
Cas No.
730931-46-1
Formula
C37H42BClF2N6O6S
Shipping Condition
Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips
We do not recommend long-term storage for the solution, please use it up soon.
