IL-7, murine recombinant
Catalog No.
P1025
IL-7, lymphoid cell growth factor, expressed in E.Coli, cross-species reactive.
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Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells. IL-7 can co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Also, IL-7 stimulates the maturation of megakaryocytes and the proliferation and differentiation of NK cells.
The murine IL-7 cDNA encodes a 154 aa protein with a 25 aa signal sequence. Human and murine IL-7 is cross-species reactive. Recombinant murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
| Determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells. | ||||||
| ED50 | < 0.2 ng/ml. | |||||
| Specific activity | > 5*106 units/mg. | |||||
Quality Control & DataSheet
- View current batch:
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Purity: ≥98%, by SDS-PAGE and HPLC.
Endotoxin Level: <0.1 ng/μg
Related Biological Data
| Gene ID: | 16196 | Accession #: | P10168 |
| Alternate Names: | IL7, IL-7, Interleukin-7. | ||
| Source: | Escherichia Coli. | M.Wt: | 15.0 kDa |
| Appearance: | Lyophilized protein | Storage: | Store at -20°C |
| Formulation: | Sterile filtered and lyophilized with no additives. | ||
| Solubility: | Reconstitute in H2O to a concentration of 0.1-1.0 µg/µl. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. | ||
| Shipping Condition: | Gel pack. | Handling: | Centrifuge the vial prior to opening. |
| Usage: | For Research Use Only! Not to be used in humans. | ||