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Oridonin

Catalog No.
N1802
Anti-tumor reagent
Grouped product items
Size Price Stock Qty
10mM (in 1mL DMSO)
Special Price $27.00 Regular Price $60.00
In stock
20mg
Special Price $31.50 Regular Price $70.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Oridonin has potent anti-tumor activity. Oridonin targets AE (AML1-ETO) oncoprotein. Exposure to oridonin induces apoptosis in AE-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt364.43
Cas No.28957-04-2
FormulaC20H28O6
Solubilityinsoluble in H2O; ≥13.6 mg/mL in DMSO; ≥4.9 mg/mL in EtOH
Chemical Name(1S,5S,6aS,9S,11bR)-1,5,6,14-tetrahydroxy-4,4-dimethyl-8-methylenedecahydro-1H-6,11b-(epoxymethano)-6a,9-methanocyclohepta[a]naphthalen-7(8H)-one
SDFDownload SDF
Canonical SMILES[H][C@@]12C(C)(C)CC[C@H](O)[C@@]1(CO3)[C@@]4([H])[C@@]([C@H](O)[C@H](C5=C)CC4)(C5=O)[C@@]3(O)[C@H]2O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure

Oridonin