RAD51 Inhibitor B02
Catalog No.
B8396
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RAD51 inhibitor B02 (B02) inhibits human RAD51 with IC50 of 27.4 μM. In vitro, the RAD51 inhibitor B02 specifically inhibits human RAD51 (IC50 = 27.4 μM), but does not inhibit its E. coli homologous RecA (IC50> 250 μM). In vivo, B02 can significantly enhance the therapeutic effect of cisplatin on tumor cells.
| Storage | Store at -20°C |
| M.Wt | 339.39 |
| Cas No. | 1290541-46-6 |
| Formula | C22H17N3O |
| Synonyms | B02 |
| Solubility | ≥24.85 mg/mL in DMSO |
| Chemical Name | (E)-3-benzyl-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one |
| SDF | Download SDF |
| Canonical SMILES | O=C(N1CC2=CC=CC=C2)C3=C(C=CC=C3)N=C1/C=C/C4=CC=CN=C4 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
