Recombinant Human Galectin-1
Human Galectin-1 also named BHL, Galaptin, GBP, L-14 and LGALS1, is belonging to the galectins family and it is encoded bythe LGALS1 gene in human. Galectin-1 is expressed by the endometrial stromal cells throughout the menstrual cycle. Galectin-1contains a single carbohydrate recognition domain through which it can bind glycans both as a monomer and as a homodimer.Dimers are non-covenantly bound and will spontaneously disassociate in low concentration. Galectin-1 may act as an autocrinenegative growth factor that regulates cell proliferation. Galectin-1 is thought to play a role in the immunosuppression required fora successful pregnancy. Human Galectin-1 shares 88 %-90 % amino acid sequence identity with rat and mouse.
Reference
| Accession # | P1229 |
| Alternate Names | BHL、Galaptin、GBP、L-14、LGALS1 |
| Source | Escherichia coli. |
| Protein sequence | ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFNAHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKLPDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD |
| M.Wt | 14.6 kDa |
| Appearance | Solution protein |
| Stability & Storage | Avoid repeated freeze-thaw cycles It is recommended that hat the protein be aliquoted for optimal storage - 12 months from date of receipt, -20 to -7°C as supplied. |
| Concentration | 0.1-1.0 mg/mL |
| Formulation | Dissolved in Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. This solution can be diluted into other aqueous buffers. |
| Biological Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 1.0-10 ng/ml. |
| Shipping Condition | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Handling | Centrifuge the vial prior to opening. |
| Usage | For Research Use Only! Not to be used in humans. |
Quality Control & DataSheet
- View current batch:
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Purity > 95%, determined by SDS-PAGE.
- Datasheet
Endotoxin: <1 EU per 1 ug of the protein by the LAL method.