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  • Search results for: 'cdk4 inhibitor'

Search results for: 'cdk4 inhibitor'

Items 191-200 of 345

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  1. CYC116
    A4125 CYC116
    Target: Aurora Kinases|FLT3|VEGFR
    Summary: Potent Aurora A/B inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
  2. 5-Azacytidine
    A1907 5-Azacytidine
     6 Citation
    Target: DNA Methyltransferases
    Summary: DNA methyltransferase inhibitor.
      insoluble in EtOH; ≥24.45 mg/mL
  3. EPZ005687
    A4171 EPZ005687
     2 Citation
    Target: EZH2
    Summary: EZH2 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
  4. Cercosporamide
    A4511 Cercosporamide
    Target: JAK|MNK
    Summary: Mnk2 and JAK3 inhibitor
      soluble in DMSO
  5. Tranylcypromine hydrochloride
    B7514 Tranylcypromine hydrochloride
     1 Citation
    Summary: Monoamine oxidase inhibitor
      ≥54.3 mg/mL
  6. SGI-1776 free base
    A4192 SGI-1776 free base
     3 Citation
    Summary: Pim kinase inhibitor,ATP-competitive
      ≥40.5 mg/mL
  7. XL228
    A3939 XL228
    Summary: IGF1R/AURORA /FGFR1-3/ABL/SRC family kinases inhibitor
      ≥21.9 mg/mL
  8. MLN8237 (Alisertib)
    A4110 MLN8237 (Alisertib)
     6 Citation
    Summary: Aurora A Kinase inhibitor, Potent and selective
      ≥25.95 mg/mL
  9. WP1066
    A4140 WP1066
    Target: STAT|JAK
    Summary: JAK2/STAT3 inhibitor,cell-permeable
      insoluble in H2O; ≥17.8 mg/mL
  10. Lestaurtinib
    A4513 Lestaurtinib
     1 Citation
    Summary: JAK2/FLT3/TrkA inhibitor
      Soluble in DMSO

Items 191-200 of 345

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  1. Category Chromatin/Epigenetics Remove This Item
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Category
  1. Bromodomain 34item
  2. Aurora Kinase 30item
  3. DNA Methyltransferase 6item
  4. HDAC 55item
  5. Histone Acetyltransferases 15item
  6. Histone Demethylases 22item
  7. Histone Methyltransferase 41item
  8. HIF 11item
  9. JAK 41item
  10. MBT Domains 1 item
  11. PARP 31item
  12. Pim 8item
  13. Protein Ser/Thr Phosphatases 29item
  14. RNA Polymerase 3item
  15. Sirtuin 14item
  16. Sphingosine Kinase-2 1 item
  17. Polycomb repressive complex 1 item
  18. SUMOylation 2item
  19. PAD 1 item
Specificity
  1. Selective 104item
Reversibility
  1. Reversible 7item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 33item
  3. PI3K 1 item
  4. Aurora Kinases 21item
  5. EZH2 3item
  6. Bromodomains 8item
  7. FLT3 5item
  8. PLK 1 item
  9. VEGFR 3item
  10. RET 1 item
  11. Hydrolase 1 item
  12. MEK 1 item
  13. DOT1L 3item
  14. FGFR 2item
  15. Nrf2 1 item
  16. Pim 3item
  17. Sir2-like Family Deacetylases (Sirtuins) 3item
  18. Src 4item
  19. Trk Receptors 1 item
  20. STAT 2item
  21. EGFR 2item
  22. Hypoxia Inducible Factors (HIFs) 2item
  23. Tankyrases 1 item
  24. JAK 20item
  25. p300 1 item
  26. Syk 1 item
  27. EZH1 1 item
  28. TNKS 1 item
  29. ErbB 1 item
  30. DNA Methyltransferases 3item
  31. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  32. SMYD2 1 item
  33. CREBBP 2item
  34. EP300 2item
  35. LRRK2 1 item
  36. PARP 8item
  37. ALK 1 item
  38. Bromodomain and Extra-Terminal motif (BET) 1 item
  39. phosphatases 1 item
  40. NAT10 1 item
  41. G9a 2item
  42. Hck 1 item
  43. SETD7 1 item
  44. MNK 1 item
  45. AChE 1 item
  46. Catechol O-Methyltransferase (COMT) 1 item
  47. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  48. Protein Arginine Methyltransferases 1 item
  49. Cytidine deaminases 1 item
  50. c-RET 1 item
  51. VEGFR3/FLT4 1 item
  52. NTRK1/TRKA 1 item
  53. CSF-1R/c-Fms 1 item
  54. PTP 1 item
  55. Protein polybromo-1 1 item
  56. SMARCA4 1 item
  57. SMARCA2 1 item
  58. p53 1 item
  59. HDAC 2item
  60. KDM 2item
  61. Histone Acetyltransferases (HATs) 2item
  62. Trx 1 item
  63. HIF-PH 1 item
  64. L3MBTL 1 item
  65. TYK2 2item
  66. MUSK 1 item
  67. MAP3K 1 item
  68. Lck 1 item
  69. p21 1 item
  70. PHF 1 item
  71. FGR 1 item
  72. YES 1 item
  73. Fyn 1 item
  74. ARG 1 item
  75. LSD 1 item
  76. PRMT 1 item
  77. GLP 1 item
  78. SK 1 item
  79. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 116item
  2. Cell Experiments 96item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 8item
  3. Bladder Cancer 2item
  4. Bladder Carcinoma 1 item
  5. Breast Cancer 19item
  6. Cancer 82item
  7. Castration-resistant Prostate Cancer 1 item
  8. Cervical Cancer 2item
  9. Chronic Lymphocytic Leukemia 1 item
  10. Colon Cancer 11item
  11. Colon Carcinoma 1 item
  12. Colorectal Cancer 5item
  13. Diabetes 1 item
  14. Diffuse Large B-cell Lymphoma 1 item
  15. Dyskinesia 1 item
  16. Epilepsy 1 item
  17. Friedreich's Ataxia 1 item
  18. Glioblastoma 2item
  19. Glioma 2item
  20. Hepatic Cancer 1 item
  21. Hepatocellular Carcinoma 1 item
  22. HIV 2item
  23. HIV Infections 2item
  24. Immunological Diseases 1 item
  25. Inflammatory Bowel Disease 1 item
  26. Inflammatory Diseases 3item
  27. Leukemia 7item
  28. Lung Cancer 6item
  29. Lymphoma 6item
  30. Melanoma 5item
  31. Mixed Lineage Leukemia 3item
  32. Multiple Myeloma 5item
  33. Myelofibrosis 1 item
  34. Myeloma 1 item
  35. Neuroblastoma 2item
  36. Neuronal Protection 1 item
  37. Non-small Cell Lung Cancer 5item
  38. Ovarian Cancer 5item
  39. Pancreatic Cancer 4item
  40. Prostate Cancer 12item
  41. Psoriasis 1 item
  42. Renal Cancer 1 item
  43. Renal Cell Carcinoma 2item
  44. Rheumatoid Arthritis 3item
  45. Thyroid Cancer 1 item