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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 1-10 of 23

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  1. COTI-2
    C4483 COTI-2
    Summary: activates mutant forms of p53
      ≤1 mg/mL
  2. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL
  3. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  4. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL
  5. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL
  6. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  7. RITA (NSC 652287)
    A4202 RITA (NSC 652287)
    Summary: Mdm2-p53 interaction and p53 ubiquitination blocking
      insoluble in H2O; ≥14.6 mg/mL
  8. MIRA-1
    A4479 MIRA-1
    Summary: Restorer of wild-type p53 conformation/cellular function
      Soluble in DMSO
  9. Nutlin-3a chiral
    A3671 Nutlin-3a chiral
     2 Citation
    Summary: MDM2 inhibitor, antiproliferative and antiproapoptotic
      ≥29.07 mg/mL
  10. Plumbagin
    A4456 Plumbagin
    Summary: Anticancer agent

Items 1-10 of 23

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