MIRA-1
Catalog No.
A4479
Restorer of wild-type p53 conformation/cellular function
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Restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent manner in vitro (IC50 = 10μM).
Physical Appearance | A white to off-white solid |
Storage | Store at 4°C |
M.Wt | 183.16 |
Cas No. | 72835-26-8 |
Formula | C8H9NO4 |
Solubility | Soluble in DMSO |
Chemical Name | (2,5-dioxopyrrol-1-yl)methyl propanoate |
SDF | Download SDF |
Canonical SMILES | CCC(=O)OCN1C(=O)C=CC1=O |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
