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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 1-10 of 133

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  1. ABT-263 (Navitoclax)
    A3007 ABT-263 (Navitoclax)
     15 Citation
    Target: Bcl-2|Bcl-w
    Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
      ≥48.73 mg/mL
  2. Obatoclax mesylate (GX15-070)
    A4194 Obatoclax mesylate (GX15-070)
     1 Citation
    Target: Bcl-2
    Summary: Potent Bcl-2 inhibitor
      insoluble in H2O; ≥20.7 mg/mL
  3. Sabutoclax
    A4199 Sabutoclax
     2 Citation
    Target: Bcl-2|Mcl-1|Bfl-1
    Summary: pan-Bcl-2 inhibitor
      insoluble in H2O; ≥205.6 mg/mL
  4. TW-37
    A4234 TW-37
     1 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
      insoluble in H2O; ≥19.75 mg/mL
  5. HA14-1
    A8168 HA14-1
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and cell-permeable
      insoluble in H2O; ≥20.45 mg/mL
  6. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL
  7. Bax inhibitor peptide V5
    A4461 Bax inhibitor peptide V5
    Target: Bax
    Summary: Bax inhibitor
      ≥29.35 mg/mL
  8. PHA-767491
    A3721 PHA-767491
    Target: Cyclin-Dependent Kinases|MK2|Cdc7
    Summary: Cdc7/cdk9 inhibitor, potent, ATP-competitive
      insoluble in H2O; insoluble in EtOH; ≥10.65 mg/mL
  9. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL
  10. PAC-1
    A8177 PAC-1
     1 Citation
    Target: Caspases
    Summary: Procaspase-3 activator
      insoluble in H2O; ≥13.4 mg/mL

Items 1-10 of 133

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  1. Signaling Pathways 128item
  2. Natural Products 3item
  3. Lab Reagents 1 item
Specificity
  1. Selective 87item
Reversibility
  1. Reversible 9item
  2. Irreversible 5item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 8item
  3. Proteasome 1 item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 4item
  6. Akt 4item
  7. Bcl-2 7item
  8. PI3K 2item
  9. Raf 4item
  10. Aurora Kinases 4item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. MDM2 1 item
  14. EZH2 1 item
  15. mTOR 2item
  16. Bromodomains 1 item
  17. AP-1 1 item
  18. MMP 1 item
  19. DT-diaphorases 1 item
  20. FLT3 3item
  21. GSK-3 2item
  22. PLK 3item
  23. Chk 1 item
  24. Eph Receptors 2item
  25. VEGFR 17item
  26. PDGFR 7item
  27. c-Kit 4item
  28. RET 1 item
  29. Phosphodiesterases (PDEs) 1 item
  30. Mcl-1 3item
  31. Thymidylate Synthase 1 item
  32. Bcr-Abl 3item
  33. MEK 4item
  34. DOT1L 1 item
  35. FGFR 3item
  36. MET 3item
  37. Src 2item
  38. RARs 1 item
  39. Trk Receptors 1 item
  40. STAT 2item
  41. EGFR 5item
  42. FAK 2item
  43. JAK 6item
  44. EZH1 1 item
  45. DNA-PK 1 item
  46. HSP90 2item
  47. Cytochrome P450 (CYP450) 1 item
  48. ErbB 1 item
  49. DNA Methyltransferases 1 item
  50. ERK 1 item
  51. c-MET 2item
  52. PKC 3item
  53. Pyk2 2item
  54. Insulin and Insulin-like Receptors 1 item
  55. PARP 2item
  56. Pyruvate dehydrogenases (PDH) 1 item
  57. ALK 1 item
  58. PKG 1 item
  59. PKA 4item
  60. AdipoR2 1 item
  61. MK2 1 item
  62. Tie-2 2item
  63. RSK 1 item
  64. Autophagy 1 item
  65. COX 2item
  66. Guanine nucleotide exchange factors (GEFs) 1 item
  67. 20S proteasomal chymotrypsin 1 item
  68. Geranylgeranyltransferase I 1 item
  69. Farnesyltransferase 1 item
  70. Nampt 1 item
  71. eIF4F 1 item
  72. Glutaminases 1 item
  73. MAGL 1 item
  74. P110 1 item
  75. Hck 1 item
  76. Opioid receptors 1 item
  77. FoxM1 1 item
  78. MNK 1 item
  79. eEF-2 1 item
  80. Cdc7 1 item
  81. CMV 1 item
  82. ZAP-70 1 item
  83. Hexokinases 1 item
  84. Flk-1 1 item
  85. Cytidine deaminases 1 item
  86. angiogenesis 1 item
  87. c-RET 1 item
  88. p70 rsk 1 item
  89. Microtubule/Tubulin 1 item
  90. Bfl-1 1 item
  91. p53-MDM2 interaction 1 item
  92. KDR 2item
  93. p53 3item
  94. HDAC 1 item
  95. HDM2 ubiquitin ligase 1 item
  96. DNA Alkylating 1 item
  97. ErbB-2 1 item
  98. PDK-1 1 item
  99. Prk 1 item
  100. HSP70 1 item
  101. Flk1 2item
  102. DHFR 1 item
  103. GARFT 1 item
  104. RHA 1 item
  105. Bcl-w 1 item
  106. SK 1 item
  107. PPK 1 item
  108. c-Syk 1 item
  109. CDK1/CyclinB 1 item
  110. Substance P/NK1 Receptor 1 item
  111. Bax 1 item