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Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

A8236 Regorafenib

4 Citation

Target: Raf|VEGFR|PDGFR|c-Kit|RET

Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1

≥25.04 mg/mL
A5573 Pimasertib (AS-703026)

Target: MEK

Summary: MEK1/2 inhibitor

≥21.55 mg/mL
A8219 Gefitinib (ZD1839)

3 Citation

Target: EGFR

Summary: Selective EGFR inhibitor

≥22.34 mg/mL
B1437 PF-477736

Target: Chk

Summary: Chk1 inhibitor

insoluble in EtOH; insoluble in H2O; ≥5.24 mg/mL
A3802 SCH 527123

5 Citation

Target: CXCR

Summary: CXCR1 and CXCR2 receptors antagonist
A1947 MEK162 (ARRY-162, ARRY-438162)

Target: MEK

Summary: MEK1/2 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; insoluble in DMSO
A8446 Ibuprofen

Target: COX

Summary: inhibitor of cyclooxygenase 1 and cyclooxygenase 2

insoluble in H2O; ≥10.31 mg/mL
B5835 AZD2932

Target: FLT3|VEGFR|PDGFR|c-Kit

Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit

Soluble in DMSO
A2168 Dovitinib (TKI-258, CHIR-258)

2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
A1882 Cediranib (AZD217)

Target: VEGFR

Summary: VEGFR inhibitor receptor,highly potent

≥22.52 mg/mL