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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

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  1. ABT-263 (Navitoclax)
    A3007 ABT-263 (Navitoclax)
     15 Citation
    Target: Bcl-2|Bcl-w
    Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
      ≥48.73 mg/mL
  2. ABT-199
    A8194 ABT-199
     14 Citation
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and selective
      ≥43.42 mg/mL
  3. TW-37
    A4234 TW-37
     1 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
      insoluble in H2O; ≥19.75 mg/mL
  4. HA14-1
    A8168 HA14-1
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and cell-permeable
      insoluble in H2O; ≥20.45 mg/mL
  5. WEHI-539
    A3935 WEHI-539
     15 Citation
    Target: Bcl-xl
    Summary: Bcl-xL inhibitor,potent and selective
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  6. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL
  7. MIM1
    A4465 MIM1
     1 Citation
    Target: Mcl-1
    Summary: Mcl-1 Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL
  8. WEHI-539 hydrochloride
    A8634 WEHI-539 hydrochloride
     1 Citation
    Summary: Bcl-xL inhibitor,high affinity and selective
      ≥28.55 mg/mL
  9. PHA-767491
    A3721 PHA-767491
    Target: Cyclin-Dependent Kinases|MK2|Cdc7
    Summary: Cdc7/cdk9 inhibitor, potent, ATP-competitive
      insoluble in H2O; insoluble in EtOH; ≥10.65 mg/mL
  10. IKK-2 inhibitor VIII
    A3485 IKK-2 inhibitor VIII
    Summary: IKK-2 inhibitor,potent and selective
      Soluble in DMSO

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  1. Signaling Pathways 178item
  2. Natural Products 5item
  3. Lab Reagents 2item
Reversibility
  1. Reversible 12item
  2. Irreversible 7item
Target
  1. Caspases 5item
  2. Cyclin-Dependent Kinases 6item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 2item
  5. Cathepsins 2item
  6. Histone Deacetylases (HDACs) 4item
  7. Inhibitor of apoptosis proteins (IAP) 1 item
  8. Akt 1 item
  9. Bcl-2 5item
  10. PI3K 2item
  11. CXCR 2item
  12. Raf 2item
  13. Aurora Kinases 5item
  14. Bcl-xl 3item
  15. CSF-1R 1 item
  16. MDM2 1 item
  17. EZH2 1 item
  18. mTOR 3item
  19. Bromodomains 2item
  20. AP-1 2item
  21. MMP 3item
  22. Myosin II ATPases 1 item
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  24. FLT3 4item
  25. GSK-3 1 item
  26. Factor Xa 1 item
  27. Farnesoid X receptors (FXRs) 1 item
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  29. Chk 1 item
  30. Eph Receptors 2item
  31. VEGFR 12item
  32. PDGFR 6item
  33. c-Kit 3item
  34. RET 1 item
  35. Phosphodiesterases (PDEs) 2item
  36. Mcl-1 3item
  37. p38 1 item
  38. PKB 1 item
  39. Bcr-Abl 2item
  40. MEK 6item
  41. DOT1L 1 item
  42. FGFR 2item
  43. Pim 1 item
  44. Voltage-gated Sodium (NaV) Channels 1 item
  45. MET 3item
  46. Src 3item
  47. RARs 1 item
  48. Trk Receptors 2item
  49. STAT 1 item
  50. EGFR 4item
  51. ROCK 1 item
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  53. JAK 5item
  54. EZH1 1 item
  55. DNA-PK 2item
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  63. Pyk2 2item
  64. 5-HT2 Receptors 1 item
  65. LRRK2 3item
  66. Insulin and Insulin-like Receptors 2item
  67. PARP 1 item
  68. Sphingosine kinases (SphKs) 1 item
  69. D1 and D5 Receptors 1 item
  70. D2 Receptors 1 item
  71. AdipoR2 1 item
  72. MK2 1 item
  73. Tie-2 2item
  74. phosphatases 1 item
  75. ATM/ATR 1 item
  76. COX 6item
  77. CK2 2item
  78. Guanine nucleotide exchange factors (GEFs) 1 item
  79. 20S proteasomal chymotrypsin 1 item
  80. Geranylgeranyltransferase I 1 item
  81. Farnesyltransferase 1 item
  82. eIF4F 1 item
  83. NADPH Oxidases 2item
  84. Calcium-activated chloride channels (CaCC) 1 item
  85. GPR35 1 item
  86. MAGL 1 item
  87. Na /K ATPases 1 item
  88. P110 1 item
  89. Hck 1 item
  90. Opioid receptors 1 item
  91. Phospholipases 1 item
  92. TRP Channel 3item
  93. FoxM1 1 item
  94. M2 Receptors 1 item
  95. Glucocorticoid Receptors 1 item
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  97. 15-lipoxygenases 1 item
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  99. Inward Rectifier Potassium (Kir) Channels 1 item
  100. Cdc7 1 item
  101. CMV 1 item
  102. ZAP-70 1 item
  103. Hexokinases 1 item
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  105. Cytidine deaminases 1 item
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  107. Glucagon Receptors 1 item
  108. DPP-4 2item
  109. c-RET 1 item
  110. FPTase 1 item
  111. p53-MDM2 interaction 1 item
  112. PARs 1 item
  113. c-Fms tyrosine kinase 1 item
  114. PAR 1 item
  115. STK 1 item
  116. IKK 1 item
  117. HCV polymerase 2item
  118. Lyn kinase 1 item
  119. Ftase 1 item
  120. PC-PLC 1 item
  121. cannabinoid receptor 1 item
  122. Rev-Erb Receptors 1 item
  123. Histone Acetyltransferases (HATs) 1 item
  124. DCLK2 1 item
  125. Lck 1 item
  126. PKD 1 item
  127. Bcl-w 1 item
  128. SK 1 item
  129. MST 1 item
  130. Substance P/NK1 Receptor 1 item
  131. gp120/CD4 1 item
  132. MTH1 1 item
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