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  • Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

Items 31-40 of 151

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  1. Tenovin-6
    A8302 Tenovin-6
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT inhibitor and p53 activator
      ≥22.75 mg/mL
  2. CX-6258
    A3337 CX-6258
    Summary: Pan-Pim kinases Inhibitor
      insoluble in EtOH; ≥11.15 mg/mL
  3. CYT387 sulfate salt
    A3339 CYT387 sulfate salt
    Summary: JAK1/JAK2 inhibitor
      Soluble in DMSO
  4. Ruxolitinib phosphate
    A3781 Ruxolitinib phosphate
    Summary: JAK1/JAK2 inhibitor
      ≥20.2 mg/mL
  5. SRT2104 (GSK2245840)
    A3821 SRT2104 (GSK2245840)
     1 Citation
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT1 activator,selective
      insoluble in H2O; insoluble in EtOH; ≥6.46 mg/mL
  6. (-)-JQ1
    A8181 (-)-JQ1
     4 Citation
    Target: Bromodomains
    Summary: Stereoisomer of (+)-JQ1, used as negative control
      ≥22.85 mg/mL
  7. WHI-P97
    A3936 WHI-P97
    Summary: Janus kinase (JAK)-3 inhibitor
      Soluble in DMSO
  8. ABT-888 (Veliparib)
    A3002 ABT-888 (Veliparib)
     6 Citation
    Summary: Potent PARP inhibitor
  9. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  10. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL

Items 31-40 of 151

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  1. Category Chromatin/Epigenetics Remove This Item
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Category
  1. Bromodomain 7item
  2. Aurora Kinase 19item
  3. DNA Methyltransferase 6item
  4. HDAC 26item
  5. Histone Acetyltransferases 1 item
  6. Histone Demethylases 1 item
  7. Histone Methyltransferase 12item
  8. HIF 8item
  9. JAK 22item
  10. MBT Domains 1 item
  11. PARP 17item
  12. Pim 7item
  13. Protein Ser/Thr Phosphatases 16item
  14. RNA Polymerase 3item
  15. Sirtuin 6item
Specificity
  1. Selective 58item
Reversibility
  1. Reversible 2item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 21item
  3. Aurora Kinases 16item
  4. EZH2 2item
  5. Bromodomains 4item
  6. FLT3 5item
  7. VEGFR 2item
  8. RET 1 item
  9. Hydrolase 1 item
  10. MEK 1 item
  11. DOT1L 1 item
  12. FGFR 1 item
  13. Nrf2 1 item
  14. Pim 2item
  15. Sir2-like Family Deacetylases (Sirtuins) 4item
  16. PP1 1 item
  17. PP2A 1 item
  18. Src 3item
  19. Trk Receptors 1 item
  20. STAT 2item
  21. EGFR 1 item
  22. Hypoxia Inducible Factors (HIFs) 1 item
  23. JAK 10item
  24. Topoisomerases 1 item
  25. ErbB 1 item
  26. DNA Methyltransferases 3item
  27. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  28. CREBBP 2item
  29. EP300 2item
  30. LRRK2 1 item
  31. PARP 2item
  32. ALK 1 item
  33. phosphatases 1 item
  34. G9a 1 item
  35. Hck 1 item
  36. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  37. Cytidine deaminases 1 item
  38. PP4 1 item
  39. c-RET 1 item
  40. VEGFR3/FLT4 1 item
  41. NTRK1/TRKA 1 item
  42. CSF-1R/c-Fms 1 item
  43. PTP 1 item
  44. p53 1 item
  45. HDAC 1 item
  46. Histone Acetyltransferases (HATs) 1 item
  47. Trx 1 item
  48. TYK2 1 item
  49. MUSK 1 item
  50. MAP3K 1 item
  51. Lck 1 item
  52. p21 1 item
  53. FGR 1 item
  54. YES 1 item
  55. Fyn 1 item
  56. ARG 1 item
  57. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 67item
  2. Cell Experiments 56item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. Bladder Cancer 2item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 13item
  5. Cancer 51item
  6. Cervical Cancer 2item
  7. Chronic Lymphocytic Leukemia 1 item
  8. Colon Cancer 7item
  9. Colorectal Cancer 4item
  10. Diabetes 1 item
  11. Glioblastoma 2item
  12. Glioma 2item
  13. Hepatic Cancer 1 item
  14. Hepatocellular Carcinoma 1 item
  15. HIV 2item
  16. HIV Infections 1 item
  17. Inflammatory Diseases 1 item
  18. Leukemia 3item
  19. Lung Cancer 4item
  20. Lymphoma 2item
  21. Melanoma 1 item
  22. Mixed Lineage Leukemia 1 item
  23. Multiple Myeloma 3item
  24. Myelofibrosis 1 item
  25. Myeloma 1 item
  26. Neuroblastoma 1 item
  27. Neuronal Protection 1 item
  28. Non-small Cell Lung Cancer 2item
  29. Ovarian Cancer 5item
  30. Pancreatic Cancer 2item
  31. Prostate Cancer 10item
  32. Psoriasis 1 item
  33. Renal Cancer 1 item
  34. Renal Cell Carcinoma 2item
  35. Rheumatoid Arthritis 2item
  36. Thyroid Cancer 1 item
  37. Type 2 Diabetes 2item