Ruxolitinib phosphate
Catalog No.
A3781
JAK1/JAK2 inhibitor
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INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor .(IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively).INCB018424 is useful for rheumatoid arthritis.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 404.36 |
| Cas No. | 1092939-17-7 |
| Formula | C17H21N6O4P |
| Synonyms | INCB018424 phosphate;INCB 018424 phosphate;INCB-018424 phosphate;Ruxolitinib |
| Solubility | ≥20.2 mg/mL in DMSO; ≥6.92 mg/mL in EtOH with gentle warming and ultrasonic; ≥8.03 mg/mL in H2O with gentle warming and ultrasonic |
| Chemical Name | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid |
| SDF | Download SDF |
| Canonical SMILES | [HH].C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OOP(=O)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
