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  • Search results for: 'research area jak stat signaling stat'

Search results for: 'research area jak stat signaling stat'

Items 11-20 of 290

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  1. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  2. AZ 960
    A4144 AZ 960
    Target: JAK
    Summary: JAKs inhibitor
      Soluble in DMSO
  3. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  4. KY 02111
    A8213 KY 02111
    Summary: WNT signaling inhibitor
      insoluble in H2O; ≥18.85 mg/mL
  5. STAT5 Inhibitor
    C4105 STAT5 Inhibitor
    Summary: STAT5 inhibitor
      ≥9.58 mg/mL
  6. CYT387
    A4143 CYT387
     1 Citation
    Summary: JAK-1/-2 inhibitor,ATP competitive
      insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL
  7. AZD1480
    A4137 AZD1480
    Target: JAK
    Summary: JAK2 inhibitor,ATP-competitive and novel
      insoluble in H2O; ≥93.8 mg/mL
  8. Ruxolitinib phosphate
    A3781 Ruxolitinib phosphate
    Summary: JAK1/JAK2 inhibitor
      ≥20.2 mg/mL
  9. TG101348 (SAR302503)
    A4136 TG101348 (SAR302503)
     2 Citation
    Target: FLT3|JAK|c-RET
    Summary: JAK-2 inhibitor,potent and selective
      ≥26.23 mg/mL
  10. JANEX-1
    A3515 JANEX-1
    Summary: JAK3 inhibitor
      insoluble in EtOH; ≥11.65 mg/mL

Items 11-20 of 290

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  1. Proteases 4item
  2. Apoptosis 10item
  3. Chromatin/Epigenetics 44item
  4. Metabolism 5item
  5. MAPK Signaling 34item
  6. Tyrosine Kinase 20item
  7. DNA Damage/DNA Repair 7item
  8. PI3K/Akt/mTOR Signaling 58item
  9. Microbiology & Virology 1 item
  10. Cell Cycle/Checkpoint 6item
  11. Ubiquitination/ Proteasome 2item
  12. JAK/STAT Signaling 46item
  13. TGF-β / Smad Signaling 22item
  14. GPCR/G protein 2item
  15. Stem Cell 39item
  16. Membrane Transporter/Ion Channel 3item
  17. Cancer Biology 12item
  18. Endocrinology and Hormones 16item
  19. Neuroscience 17item
  20. Obesity, Appetite Control & Diabetes 4item
  21. Other Signal Transduction 42item
  22. Others 12item
  23. Immunology/Inflammation 8item
  24. Cardiovascular 24item
Specificity
  1. Selective 92item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 8item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Akt 9item
  3. PI3K 13item
  4. Raf 8item
  5. Aurora Kinases 1 item
  6. mTOR 8item
  7. Androgen Receptors 1 item
  8. FLT3 2item
  9. GSK-3 7item
  10. P-glycoprotein (P-gp) 1 item
  11. VEGFR 6item
  12. PDGFR 1 item
  13. Phosphodiesterases (PDEs) 1 item
  14. p38 4item
  15. PKB 1 item
  16. JNK 4item
  17. MEK 5item
  18. PORCN 1 item
  19. FGFR 2item
  20. Nrf2 1 item
  21. GABAB Receptors 1 item
  22. Smoothened 1 item
  23. Src 1 item
  24. Trk Receptors 1 item
  25. NMDA Receptors 1 item
  26. STAT 6item
  27. EGFR 4item
  28. Hedgehog 1 item
  29. BMP and Other Activin Receptors 2item
  30. JAK 19item
  31. Syk 2item
  32. DNA-PK 1 item
  33. HSP90 1 item
  34. TNKS 1 item
  35. Toll-like receptors (TLRs) 1 item
  36. ERK 2item
  37. PKC 6item
  38. Melanocortin (MC) Receptors 1 item
  39. ALK 2item
  40. PKG 1 item
  41. PKA 4item
  42. Fatty-acid-binding proteins (FABPs) 1 item
  43. RSK 1 item
  44. Histamine H1 Receptors 1 item
  45. MNK 1 item
  46. NO Donors / Precursors 1 item
  47. IL Receptors 1 item
  48. AChE 1 item
  49. BACE 1 item
  50. c-RET 1 item
  51. p70 rsk 1 item
  52. sodium channels 1 item
  53. Smoothened receptor 1 item
  54. Nrf2/ARE signal 1 item
  55. PPAR 1 item
  56. Antibiotic 1 item
  57. Prk 1 item
  58. ICAM 1 item
  59. Rho 1 item
  60. TYK2 2item
  61. MUSK 1 item
  62. MAP3K 1 item
  63. Thrombin Receptor 1 item
  64. prolactin secretion 1 item
  65. gonadotropin release 1 item
  66. TRPC channel 1 item
  67. FKBP 1 item
Reported Experiments
  1. Animal Experiments 126item
  2. Cell Experiments 100item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 3item
  3. Bladder Cancer 1 item
  4. Breast Cancer 19item
  5. Cancer 78item
  6. Cervical Cancer 2item
  7. Colon Cancer 8item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 9item
  10. Glioblastoma 10item
  11. Glioma 3item
  12. Heart Failure 1 item
  13. HIV Infections 1 item
  14. Immunological Diseases 1 item
  15. Inflammatory Bowel Disease 1 item
  16. Leukemia 9item
  17. Liver Cancer 1 item
  18. Lung Cancer 7item
  19. Lymphoma 3item
  20. Melanoma 6item
  21. Multiple Myeloma 1 item
  22. Myelofibrosis 1 item
  23. Myeloma 1 item
  24. Neuroblastoma 2item
  25. Non-small Cell Lung Cancer 5item
  26. Ovarian Cancer 6item
  27. Pancreatic Cancer 9item
  28. Pancreatic Carcinoma 2item
  29. Prostate Cancer 11item
  30. Psoriasis 1 item
  31. Pulmonary Arterial Hypertension 1 item
  32. Pulmonary Fibrosis 1 item
  33. Renal Cancer 1 item
  34. Rheumatoid Arthritis 4item
  35. Thyroid Cancer 2item
  36. Type 2 Diabetes 2item