VSV-G Peptide
VSV-G , a vesicular stomatitis virus G (VSV-G) protein fragment. VSV-G protein is commonly used in biomedical research to pseudotype retroviral and lentiviral vectors, conveying the ability to transduce a broad range of mammalian cell types with genes of interest. [1] The VSIV G protein has also been used in cytological studies of trafficking in the endomembrane system. Immunoelectron microscopy suggests that VSIV G protein moves from cis to trans Golgi bodies without being transported between them in vesicles, supporting the cisternal maturation model of Golgi trafficking. [2]
References:
1. Cronin J, Zhang XY, Reiser J (2005). "Altering the tropism of lentiviral vectors through pseudotyping". Curr Gene Ther 5 (4): 387–98.
2. Mironov AA, Beznoussenko GV, Nicoziani P, Martella O, Trucco A, Kweon H, Giandomenico DD, Polishchuk RS, Fusella A, Lupetti P, Berger EG, Geerts WJC, Koster AJ, Burger KNJ, Luini A (2001). "Small cargo proteins and large aggregates can traverse the Golgi by a common mechanism without leaving the lumen of cisternae". JCB 155 (7): 1225–38.
| Physical Appearance | A solid |
| Storage | Desiccate at -20°C |
| M.Wt | 1339.52 |
| Formula | C57H94N16O19S |
| Synonyms | H-Tyr-Thr-Asp-Ile-Glu-Met-Asn-Arg-Leu-Gly-Lys-OH |
| Solubility | ≥134 mg/mL in DMSO; insoluble in EtOH; ≥30.6 mg/mL in H2O |
| Chemical Name | VSV-G Peptide |
| SDF | Download SDF |
| Canonical SMILES | CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=C(C=C1)O)N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| Description | VSV-G Peptide is a 11 amino acid peptide derived from the Vesicular Stomatitis viral glycoprotein. | |||||
| Targets | anti-VSV-G antibody | |||||
| IC50 | ||||||
Quality Control & MSDS
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Chemical structure
