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  • Search results for: 'research area metabolism cyp3a cyp450'

Search results for: 'research area metabolism cyp3a cyp450'

Items 1-10 of 33

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  1. Cobicistat (GS-9350)
    A4313 Cobicistat (GS-9350)
    Target: Cytochrome P450 (CYP450)
    Summary: Selective CYP3A inhibitor
      insoluble in H2O; ≥150.9 mg/mL
  2. GW9662
    A4300 GW9662
     1 Citation
    Summary: PPARγ antagonist
      insoluble in H2O; ≥13.75 mg/mL
  3. GW501516
    A4309 GW501516
     1 Citation
    Summary: PPARδ agonist,selective and potent
      insoluble in H2O; ≥18.05 mg/mL
  4. Avasimibe
    A4318 Avasimibe
    Target: Acyl coenzyme A: cholesterol acyltransferases
    Summary: ACAT inhibitor,orally bioavailable
      ≥25.09 mg/mL
  5. Vardenafil HCl Trihydrate
    A4323 Vardenafil HCl Trihydrate
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor, potent and selective
      ≥13.3 mg/mL
  6. Isotretinoin
    A4330 Isotretinoin
    Target: RARs
    Summary: Dopamine β-hydroxylase activator
      insoluble in H2O; ≥13.8 mg/mL
  7. Avanafil
    A4334 Avanafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.6 mg/mL
  8. Cilostazol
    A4337 Cilostazol
    Summary: PDE3 inhibitor
      insoluble in H2O; ≥15.4 mg/mL
  9. Pimobendan
    A4340 Pimobendan
    Target: Phosphodiesterases (PDEs)
    Summary: Selective PDE3 inhibitor.Ca2+ channel sensitizer
      insoluble in H2O; ≥16.2 mg/mL
  10. Tioxolone
    A4362 Tioxolone
    Target: Carbonic Anhydrases
    Summary: CAI inhibitor
      ≥63.2 mg/mL

Items 1-10 of 33

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